The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
COVID19-Related Onset and Relapses of Juvenile Systemic Lupus Erythematosus-Like Disease. [PDF]
Cannata C +3 more
europepmc +2 more sources
Chronic granulomatous disease associated with systemic lupus erythematosus and systemic onset juvenile idiopathic arthritis [PDF]
Chronic granulomatous disease (CGD) is a primary immune deficiency that characterized with recurrent infections and granuloma formation. A variety of autoimmune disorders and immune-mediated phenomena such as inflammatory bowel disease, discoid lupus erythematous, juvenile idiopathic arthritis, Ig A nephropathy, sarcoidosis, rheumatoid arthritis ...
Parvaneh, Vadood +3 more
openaire +1 more source
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]
Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario +4 more
core +4 more sources
RECURRENT MAJOR INFECTIONS IN JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: A CLOSE LINK WITH LONG-TERM DISEASE DAMAGE [PDF]
INTRODUCTION: Infection is a significant cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). We postulated that patients with recurrent infections are more likely to have poorer disease outcome. OBJECTIVE: The objectives of this study were to describe the pattern of infections and disease damage that ...
Lee, PPW +4 more
openaire +8 more sources
Histopathology of the gut in rheumatic diseases [PDF]
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F. +4 more
core +1 more source
PReS-FINAL-2352: Apoptosis profile in patients with juvenile-onset systemic lupus erythematosus [PDF]
Apoptosis related proteins have been involved in immune dysregulation and development of systemic lupus erythematosus (SLE).
Liphaus, B +3 more
openaire +1 more source
Differences in disease phenotype and severity in SLE across age groups [PDF]
OBJECTIVES: Significant differences have been reported in disease phenotype and severity of systemic lupus erythematosus (SLE) presenting in different age groups. Most indicate a more severe phenotype in juvenile-onset SLE (JSLE). There have been limited
Ambrose, N +6 more
core +1 more source
Inadequate dietary intake of children and adolescents with juvenile idiopathic arthritis and systemic lupus erythematosus [PDF]
OBJECTIVES: To evaluate the dietary intake of children and adolescents with juvenile idiopathic arthritis (JIA) and juvenile systemic lupus erythematosus (JSLE) using a 24-hour diet recall and relating it to the patients clinical and anthropometric ...
Caetano, Michelle Caetano +6 more
core +3 more sources
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus
Neuropsychiatric disorders in juvenile-onset systemic lupus erythematosus (SLE) stay in the focus of attention in recent decades due to significant influence of CNS lesions on SLE course in general, necessity to optimize therapeutic interventions and ...
M. I. Kaleda, I. P. Nikishina
doaj +1 more source

