Results 51 to 60 of about 28,304 (252)

Early-Onset Autoimmune Disease as a Manifestation of Primary Immunodeficiency [PDF]

, 2015
Autoimmune disorders (AID) have been increasingly observed in association with primary immunodeficiencies (PIDs). Here, we discuss the interface between PID and AID, focusing on autoimmune manifestations early in life, which can be diagnostic clues for ...
Carneiro-Sampaio, Magda, Coutinho, Antonio   +1 more
core   +2 more sources

Use of single photon emission computed tomography and magnetic resonance to evaluate central nervous system involvement in patients with juvenile systemic lupus erythematosus [PDF]

, 2002
The objective of the present study was to identify the single photon emission computed tomography (SPECT) and magnetic resonance (MR) findings in juvenile systemic lupus erythematosus (JSLE) patients with CNS involvement and to try to correlate them with
Alonso, Gilberto, Hilário, Maria Odete Esteves, Lederman, Henrique Manoel, Len, Claudio Arnaldo, Prismich, Glaucia, Quaresma, Marina Rodrigues, Sevillano, Marta Maite, Terreri, Maria Teresa Ramos Ascensão   +7 more
core   +2 more sources

Calprotectin in rheumatic diseases: a review

Rheumatology, 2016
Calprotectin also known as MRP8/14 or S100A8/A9 is a heterodimeric complex of two S100 calcium-binding proteins: myeloid-related protein 8 (MRP-8 or S100A8) and MRP-14 (or S100A9). At present, according to many authors, it is considered that calprotectin
Magdalena Kopeć-Mędrek, Małgorzata Widuchowska, Eugeniusz J. Kucharz   +2 more
doaj   +1 more source

From Childhood to Adulthood: The Trajectory of Damage in Patients With Juvenile‐Onset Systemic Lupus Erythematosus [PDF]

Arthritis Care & Research, 2017
ObjectiveTo determine the longitudinal damage trajectory of patients with juvenile‐onset systemic lupus erythematosus (SLE), and to identify baseline and disease course predictors of damage trajectory.MethodsThis is a retrospective inception cohort. Longitudinal pediatric‐age data were obtained from a juvenile‐onset SLE research database, while adult ...
Lily S H, Lim, Eleanor, Pullenayegum, Lillian, Lim, Dafna, Gladman, Brian, Feldman, Earl, Silverman   +5 more
openaire   +2 more sources

Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK

Lupus, 2021
Systemic lupus erythematosus (SLE) is a systemic autoimmune/inflammatory disease. Patients diagnosed with juvenile-onset SLE (jSLE), when compared to individuals with adult-onset SLE, develop more severe organ involvement, increased disease activity and ...
J. Massias, E. Smith, E. Al-Abadi, K. Armon, K. Bailey, Coziana Ciurtin, J. Davidson, J. Gardner-Medwin, K. Haslam, D. Hawley, A. Leahy, V. Leone, F. McErlane, D. Mewar, G. Modgil, R. Moots, C. Pilkington, A. Ramanan, S. Rangaraj, P. Riley, A. Sridhar, N. Wilkinson, M. Beresford, C. Hedrich   +23 more
semanticscholar   +1 more source

International validation of a urinary biomarker panel for identification of active lupus nephritis in children. [PDF]

, 2016
Conventional markers of juvenile-onset systemic lupus erythematosus (JSLE) disease activity fail to adequately identify lupus nephritis (LN). While individual novel urine biomarkers are good at detecting LN flares, biomarker panels may improve diagnostic
Beresford, MW, Corkhill, R, Ekdawy, D, Goilav, B, Jones, CA, Jorgensen, AL, Marks, SD, Midgley, A, Newland, P, Oni, L, Pilkington, C, Putterman, C, Rubinstein, T, Smith, EMD, Tullus, K, Wahezi, D   +15 more
core   +2 more sources

CURRENT INTERNATIONAL GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS

Научно-практическая ревматология, 2018
Systemic lupus erythematosus (SLE) with its onset in childhood or adolescence is a significant problem in the practice of pediatricians and rheumatologists due to diagnostic difficulties, clinical features, and the greater likelihood of unfavorable ...
M. I. Kaleda, I. P. Nikishina
doaj   +1 more source

The presence of high mobility group box-1 and soluble receptor for advanced glycation end-products in juvenile idiopathic arthritis and juvenile systemic lupus erythematosus [PDF]

, 2014
BACKGROUND: The involvement of high mobility group box-1 (HMGB1) in various inflammatory and autoimmune diseases has been documented but clinical trials on the contribution of this pro-inflammatory alarmin in children with juvenile idiopathic ...
Bobek, Dubravka, Grčević, Danka, Jelušić, Marija, Kovačić, Nataša, Lukić, Ivan Krešimir   +4 more
core   +1 more source

Problems of systemic connective tissue diseases of childhood in historical perspective

Научно-практическая ревматология
The relevance of study systemic connective tissue diseases with juvenile onset for modern medicine is determined by the trend towards their growth in the population, the difficulty of early diagnosis, the rapid development of disability and a poor life ...
M. I. Kaleda, I. P. Nikishina
doaj   +1 more source

Juvenile systemic lupus erythematosus presenting as pancarditis

Pediatric Rheumatology Online Journal, 2019
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with marked variation in its clinical presentation. Juvenile SLE (jSLE) accounts for 15–20% of all cases and is diagnosed when SLE manifests before 18 years of age. Pancarditis
D. O’Leary, C. O’Connor, L. Nertney, E. J. MacDermott, D. Mullane, O. Franklin, O. G. Killeen   +6 more
doaj   +1 more source