Results 91 to 100 of about 1,282,511 (265)

Nbeal2 Inactivation Triggers Abl1 Stabilisation and Dysregulated Subcellular Localisation of the Multi‐Drug‐Resistant Protein MDR1 (ABCB1) in Mast Cells

Immunology, Volume 177, Issue 2, Page 355-369, February 2026.
(A) Proposed model for Abl1 degradation via Nbeal2. Nbeal2 interacts with Abl1 with its WDR domain. This results in proteasomal degradation by a yet unidentified ubiquitin ligase. Therefore, Nbeal2 inactivation stabilises Abl1, which supports mast cell (MC) degeneration. (B) In wt MCs, the Abl1 protein level is controlled by Nbeal2. Furthermore, Nbeal2
Raphaela Marquardt, Nico Andreas, Ronja Herrnberger, Claudia Küchler, Katrin Hornung, Bernhard Nieswandt, Marco Groth, Paul M. Jordan, Oliver Werz, Julia Drube, Sebastian Drube   +10 more
wiley   +1 more source

Allergen-specific immunotherapy of Hymenoptera venom allergy:also a matter of diagnosis [PDF]

, 2015
Stings of hymenoptera can induce IgE-mediated hypersensitivity reactions in venom-allergic patients, ranging from local up to severe systemic reactions and even fatal anaphylaxis.
Schiener, Maximilian, Graessel, Anke, Ollert, Markus, Schmidt-Weber, Carsten B, Blank, Simon   +4 more
core   +2 more sources

Psychometric evaluation of the Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF©) and determination of a threshold score for moderate symptoms [PDF]

, 2023
Alan L. Shields, Fiona Taylor, Roger E. Lamoureux, Brad Padilla, Kas Severson, Tanya Green, Anthony Boral, Cem Akin, Frank Siebenhaar, Brenton G. Mar   +9 more
openalex   +1 more source

Systemic Mastocytosis Associated with “Smoldering” Multiple Myeloma

Diagnostics, 2021
A 79-year-old woman presented with a long history of peripheral eosinophilia. Previous right hemicolectomy for colonic polyposis was reported. Laboratory tests were notable for mild macrocitic anaemia and eosinophilia. β2 microglobulin and serum tryptase
M. Zanelli, S. Ricci, M. Zizzo, F. Sanguedolce, Federica De Giorgi, A. Palicelli, Giovanni Martino, S. Ascani   +7 more
semanticscholar   +1 more source

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

American Journal of Hematology, Volume 101, Issue 1, Page 110-128, January 2026.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

Routine abdominal ultrasonography has limited value in the care for patients with indolent systemic mastocytosis [PDF]

, 2017
Objectives: Systemic mastocytosis (SM) is a myeloproliferative disease characterized by the accumulation of aberrant mast cells. Since advanced subtypes of SM can lead to organ dysfunction and shortened survival, timely recognition of progressive disease
Daele, P.L.A. (Paul) van, de Mol, C.L., Gerth van Wijk, R. (Roy), Hagen, P.M. (Martin) van, Hermans, M.A.W. (Maud A.W.)   +4 more
core   +2 more sources

Practical implications of the World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Categories and ancillary testing for subtyping of hematolymphoid tumors on FNA biopsy cytopathology using a pattern‐based approach

Cancer Cytopathology, Volume 134, Issue 1, January 2026.
Abstract The objective of the recently published World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology (WHO system) is to standardize the diagnostic approach to fine‐needle aspiration biopsies of hematolymphoid tissues.
Mats Ehinger, Maria Calaminici, Immacolata Cozzolino, Pio Zeppa, Andrew S. Field   +4 more
wiley   +1 more source

[Systemic mastocytosis: a retrospective analysis of 11 cases]. [PDF]

, 2023
L. Chang, Li Zhang, Yong Zhang, Jun Feng, Daobin Zhou, Xinxin Cao   +5 more
openalex   +1 more source

Distinct Tryptase Gene Copy Number Variations Correlate With Tryptase Levels in a Population‐Based Cohort

Allergy, EarlyView.
Yannick Chantran, Simone Choi, Céline Roda, Stéphane Barete, Pierre Hirsch, Olivier Hermine, Laura Polivka, Julien Rossignol, Michel Arock, Fanny Rancière, Isabelle Momas   +10 more
wiley   +1 more source

Disodium Cromoglycate Attenuates the Depressive‐Like Behaviors in Mice by Inhibiting Neuroinflammation

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Mast cells were increased in the brain of depression model mice. Administration of Disodium Cromoglycate could alleviate depressive‐like behaviors in mice of LPS and CRS models. Administration of Disodium Cromoglycate mitigated the infiltration of mast cells in brain and down‐reuglated the expression of pro‐inflammatory factors in the brain of ...
Yun Xiao, Kaifan Liu, Zengqiang Yuan, Yajin Liao   +3 more
wiley   +1 more source