Results 111 to 120 of about 1,282,511 (265)

Value of urinary N-methylhistamine measurements m childhood mastocytosis [PDF]

, 1996
Background: Histamine is an indicator of mast cell activation. N- methylhistamine (NMH) is a metabolite of histamine that can be measured in urine. Objective: Our purpose was to assess the usefulness of determining urinary NMH levels for the diagnosis ...
De Lijster De Raadt, J. (Jacqueline), Gysel, D. (Dirk) van, Mulder, P.G.H. (Paul), Oranje, A.P. (Arnold), Toorenenbergen, A.W. (Albert) van, Vermeiden, I. (Ida)   +5 more
core   +1 more source

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

American Journal of Hematology, Volume 100, Issue 12, Page 2305-2319, December 2025.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent, Johann Wojta, Petri T. Kovanen, Olivier Hermine, Falko Fend, Karl Sotlar, Hildegard Greinix, Klaus Geissler, Karin Hartmann, Juliana Schwaab, Marco Herling, Laura Boccuni, Lukas Kazianka, Max Vincent John, Wolfgang R. Sperr, Carina Zierfuss, Alexandar Tzankov, Christian Sillaber, Milen Minkov, Gregor Hoermann, Matthew Collin, Hans‐Peter Horny, Torsten Haferlach, Maria Sibilia, Julien Haroche, Paul La Rosée, Alberto Orfao, Michel Arock   +27 more
wiley   +1 more source

Avapritinib treatment of aggressive systemic mastocytosis with a novel KIT exon 17 mutation

Leukemia Research Reports
Background: Systemic mastocytosis is a rare hematologic malignancy that leads to the accumulation of neoplastic mast cells in the bone marrow, visceral organs, and skin.
Lyndsey Sandow, Ajia Town, Michael C. Heinrich   +2 more
doaj   +1 more source

Multiple large osteolytic lesions in a patient with systemic mastocytosis: a challenging diagnosis

Clinical Case Reports, 2017
Key Clinical Message Patients with advanced variants of Systemic Mastocytosis may develop destructive bone lesions when massive mast cell (MC) infiltrates are present. Finding of large osteolyses in indolent systemic mastocytosis, typically characterized
Massimiliano Bonifacio, Roberta Zanotti, Emanuele Guardalben, Elda Mimiola, Francesca Scognamiglio, Omar Perbellini, Giovanna De Matteis, Luis Escribano, Patrizia Bonadonna, Daniela Grigolato, Sergio Bissoli, Alice Parisi, Alberto Zamò, Achille Ambrosetti, Maurizio Rossini   +14 more
doaj   +1 more source

Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis

Haematologica, 2011
Cooperating genetic events are likely to contribute to the phenotypic diversity of KIT-D816V systemic mastocytosis. In this study, 44 patients with KIT-D816V systemic mastocytosis were evaluated for coexisting NRAS, KRAS, HRAS or MRAS mutations ...
Todd M. Wilson, Irina Maric, Olga Simakova, Yun Bai, Eunice Ching Chan, Nicolas Olivares, Melody Carter, Dragan Maric, Jamie Robyn, Dean D. Metcalfe   +9 more
doaj   +1 more source

SEVERE OSTEOPOROSIS DUE TO SYSTEMIC MAST CELL DISEASE: SUCCESSFUL TREATMENT WITH INTERFERON ALPHA-2B [PDF]

, 2017
We describe a 33-yr-old man suffering from severe vertebral osteoporosis and urticaria pigmentosa due to systemic mast cell disease (SMCD). Because i.v.
BEYELER, C., DAHINDEN, C., GERBER, N. J., HUNZIKER, T., LEHMANN, T., LÄMMLE, B., OLAH, A. J., VOCK, P.   +7 more
core  

Mast cell-related disorders presenting with Kounis syndrome [PDF]

, 2016
Letter to the Editor.-- et al.Peer ...
Escribano, Luis, García-Montero, Andrés, Gonzalez-de-Olano, David, Jara-Acevedo, Maria, Matito, Almudena, Morgado, J. M., Orfao, Alberto, Sánchez-Muñoz, Laura, Teodosio, Cristina, Álvarez-Twose, Iván   +9 more
core   +1 more source

Atypical chronic myeloid leukemia: From diagnosis to molecular features and therapeutic options

HemaSphere, Volume 9, Issue 12, December 2025.
ABSTRACT Atypical chronic myeloid leukemia (aCML) is a rare form of myelodysplastic (MDS)/myeloproliferative neoplasm (MPN) overlap disorder characterized by neutrophilic leukocytosis with circulating immature myeloid cells (IMC), frequent hepatosplenomegaly, and poor prognosis with high rates of leukemic transformation.
Alessandra Iurlo, Daniele Cattaneo, Umberto Gianelli, Francesco Passamonti   +3 more
wiley   +1 more source

International consensus on (ICON) anaphylaxis [PDF]

, 2014
ICON: Anaphylaxis provides a unique perspective on the principal evidence-based anaphylaxis guidelines developed and published independently from 2010 through 2014 by four allergy/immunology organizations.
Alvarez-Twose, Antonella Muraro, Arga, Armstrong, Arroabarren, Aziz Sheikh, Barnett, Bauer, Belhocine, Ben-Shoshan, Bilo, Bonadonna, Boyce, Boyle, Brockow, Brouwers, Brown, Brown, Brown, Brown, Caffarelli, Camargo, Campbell, Campbell, Campbell, Cetinkaya, Chad, Chiang, Choo, Cox, Cummings, Dana V. Wallace, de Silva, Dhami, Duke, Edwards, Ellis, Enarson, F. Estelle R. Simons, Field, Fineman, Fleischer, Gibbison, Gibbs, Golden, Gonzalez-Perez, Grabenhenrich, Graham Roberts, Harduar-Morano, Heinzerling, Hoffer, Iribarren, Jang, Jones, Kalesnikoff, Kelleher, Khodoun, Kim, Kim, Lafuente, Landsman-Blumberg, Ledit R.F. Ardusso, Lee, Li, Lieberman, Liew, Liew, Liu, Lotvall, Ludman, Lynette P. Shek, M Beatrice Bilò, Margitta Worm, Mario Sanchez-Borges, Mertes, Minciullo, Motohiro Ebisawa, Muller, Muraro, Ng, Nicklas, Noimark, Nurmatov, Panesar, Park, Perel, Phil Lieberman, Raimer, Ralston, Renaudin, Ribeiro-Vaz, Richard F. Lockey, Rudders, Rudders, Rueff, Rueff, Sala-Cunill, Sampson, Sampson, Sanchez-Borges, Sanchez-Borges, Schneider, Sheikh, Sheikh, Shemesh, Shen, Sicherer, Sicherer, Simons, Simons, Simons, Simons, Simons, Simons, Simons, Simons, Simons, Sole, Stoevesandt, Strohmeier, Takahashi, Tanno, Techapornroong, Tejedor Alonso, Thong, Topal, Triggiani, Vadas, Vadas, Vale, Valent, Vereda, Victoria Cardona, Wolbing, Wood, Wood, Worm, Yehia M. El-Gamal   +137 more
core   +3 more sources

Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms [PDF]

, 2015
Myeloproliferative neoplasms (MPN) are a diverse group of chronic hematological disorders that involve unregulated clonal proliferation of white blood cells.
Kapur, Reuben, Pandey, Ruchi
core   +1 more source