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Genetic features of indolent and advanced forms of systemic mastocytosis
Background. Mastocytosis is a group of diseases characterized by tumor proliferation of mast cells and their accumulation in organs and tissues, including skin, hematopoietic organs (bone marrow, spleen, lymph nodes), and the gastrointestinal tract ...
D. I. Shikhbabaeva +8 more
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Systemic Mastocytosis - a Diagnostic Challenge [PDF]
Mastocytosis refers to a group of disorders characterized by the infiltration of clonally derived mast cells to the skin or extracutaneous tissues resulting in a heterogeneous clinical picture. It is a rare hematologic disorder in all its forms.
Galzerano, A +3 more
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Human Skin/SCID Mouse Chimeras as an In Vivo Model for Human Cutaneous Mast Cell Hyperplasia [PDF]
Human skin xenografted to mice with severe combined immunodeficiency syndrome (SCID) was evaluated to determine the integrity and fate of human dermal mast cells.
Melpo Christofidou-Solomidou +42 more
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Background. Mastocytosis is a very rare disease with various manifestations, based on abnormal clonal proliferation of mast cells in organs and tissues, such as: skin, bone marrow, lymph nodes, liver, spleen, and gastrointestinal tract. The diagnosis can
Timur T. Valiev +6 more
doaj +1 more source
An Adult Patient with Systemic Mastocytosis and B-Acute Lymphoblastic Leukemia
Mastocytosis is a myeloproliferative neoplasm characterized by clonal expansion of abnormal mast cells, ranging from the cutaneous forms of the disease to mast cell leukemia.
Theodoros Iliakis +13 more
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Chronic myeloid leukemia and systemic mastocytosis are myeloid neoplasms sharing a number of pathogenetic and clinical features. In both conditions, an aberrantly activated oncoprotein with tyrosine kinase activity, namely BCR-ABL1 in chronic myeloid ...
Siham Bibi +9 more
doaj +1 more source
Mast cell leukemia is a rare and aggressive form of mastocytosis characterized by >20% mast cells found in the bone marrow aspirates of patients with signs of systemic mastocytosis-related organ damage.
James Bauer, MD, PhD +2 more
doaj +1 more source
Systemic mastocytosis with concurrent multiple myeloma [PDF]
Ashvind Prabahran, Surender Juneja
openalex +1 more source
Long-Term Successful Treatment of Indolent Systemic Mastocytosis With Omalizumab [PDF]
Samuel L Weiss
openalex +1 more source

