Results 51 to 60 of about 66,314 (265)

Systemic mastocytosis in Croatia

Liječnički vjesnik, 2022
Aim: The aims of this study were to identify patients with systemic mastocytosis (SM) in Croatia and to analyze their clinical characteristics. Patients and methods: Patients with SM treated at eight hospitals in Croatia were retrospectively identified and their clinical characteristics, treatment patterns and outcomes were analyzed.
Ivan Krečak, Pavle Rončević, Marin Kursar, Marko Lucijanić, Davor Galušić, Stefan Mrđenović, Martina Morić Perić, Iva Ivanko, Hana Matijaca, Josipa Budimir, Sanja Jakelić, Ivana Karaman, Rajko Kušec   +12 more
openaire   +2 more sources

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

American Journal of Hematology, EarlyView.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

Kit receptor tyrosine kinase dysregulations in feline splenic mast cell tumours [PDF]

, 2017
This study investigated Ki t receptor dysregulations (cytoplasmic immunohistochemical expression and/or c-KIT mutations) in cats a\ufb00ected with splenic mast cell tumours. Twenty-two cats were included.
Amagai, Arock, Carpenter, Columbo, Dank, Frost, Garner, Giantin, Hadzijusufovic, Hahn, Henry, Isotani, Isotani, Lanternier, Letard, Liska, Litster, London, London, Mallett, Marconato, Meininger, Rodriguez-Cariño, Sabattini, Sabattini, Sabattini, Spangler, Takanosu, Takeuchi, Webster, Webster, Webster, Zemke   +32 more
core   +1 more source

Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten, LaTasha K. Crawford, Elise J. B. De, Wencheng Li, Yoshiyuki Akiyama   +4 more
wiley   +1 more source

Receptor tyrosine kinase and p16/CDKN2 expression in a case of tripe palms associated with non-small-cell lung cancer [PDF]

, 1999
Background: Tripe palms is a descriptive term for a cutaneous paraneoplastic keratoderma. Tripe palms are frequently associated with gastric and pulmonary carcinoma. The pathogenetic mechanism remains unknown.
Bezold, G., Dieterle, C., Greulich, K. M., Krähn, Gertraud, Peter, R. U., Wolff, H.   +5 more
core   +1 more source

Beyond the numbers: Critical analysis of the role of postmortem tryptase in the forensic diagnosis of anaphylaxis

Journal of Forensic Sciences, EarlyView.
Abstract The postmortem diagnosis of anaphylaxis remains a forensic challenge due to the lack of specific external signs. Tryptase, a mast cell‐derived protease, has emerged as a potential biomarker for fatal anaphylaxis. This systematic review critically examined 40 studies published between 2014 and 2024, including both biochemical and ...
Luca Tomassini, Giulia Ricchezze, Cristiana Gambelunghe, Massimo Lancia, Marco Gramaccia, Francesco De Micco, Piergiorgio Fedeli, Mariano Cingolani, Roberto Scendoni   +8 more
wiley   +1 more source

Difficulties of primary diagnosis in patients with suspected systemic mastocytosis

Онкогематология
Background. Mastocytosis is a rare myeloproliferative disease based on clonal hematopoiesis of mast cells, with accumulation of mast cells in various tissues and organs.
Z. K. Abdulkhalikova, M. V. Barabanshchikova, V. V. Baykov, I. M. Barkhatov, E. V. Morozova, I. S. Moiseev   +5 more
doaj   +1 more source

Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab

Case Reports in Medicine, 2015
The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti ...
Sofie Lieberoth, Simon Francis Thomsen
doaj   +1 more source

Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level

Human Vaccines & Immunotherapeutics, 2021
Mastocytosis is a rare group of disorders characterized by abnormal accumulation of mast cells in the skin, bone marrow, and internal organs. In particular, patients with systemic mastocytosis are at an increased risk of frequent and severe episodes of ...
Ali Selcuk, Abdullah Baysan
doaj   +1 more source

Regulation of mast cell function and survival in health and disease [PDF]

, 2016
Mast cells are sentinels of danger but they are also the major effector cells in allergic disease causing the well-known allergic symptoms caused by their mediators such as histamine and prostaglandin D2 that are released upon activation. Mastocytosis is
Lyberg, Katarina
core   +1 more source