Results 51 to 60 of about 68,714 (217)

French guidelines for the management of nonadvanced mastocytosis in adults

Orphanet Journal of Rare Diseases
Mastocytosis is a rare disease caused by abnormal mast cell accumulation/proliferation in various organs/tissues. Its clinical features exhibit significant variability irrespective of its clinical presentation, classification, global survival or impact ...
Cristina Bulai Livideanu, Stéphane Barete, Ghandi Damaj, Michel Arock, Julien Rossignol, Olivier Hermine   +5 more
doaj   +1 more source

Comprehensive mastocytosis data analysis from a single center

BMC Cancer, 2023
Mastocytosis is a very rare disorder and is divided into three prognostically distinct variants by World Health Organization: Cutaneous mastocytosis (CM), systemic mastocytosis (SM), and mast cell sarcoma or localized mast cell (MC) tumors.
Tarık Onur Tiryaki, Sıdıka Gülkan Özkan, Simge Erdem, Aynur Dağlar Aday, İpek Yönal Hindilerden, Aslı Gelincik, Can Baykal, Gülçin Yegen, İbrahim Öner Doğan, Nesimi Büyükbabani, Meliha Nalçacı, Akif Selim Yavuz   +11 more
doaj   +1 more source

Diagnostic and therapeutic considerations in idiopathic hypereosinophilia with warm autoimmune hemolytic anemia. [PDF]

, 2015
Hypereosinophilic syndrome (HES) encompasses numerous diverse conditions resulting in peripheral hypereosinophilia that cannot be explained by hypersensitivity, infection, or atopy and that is not associated with known systemic diseases with specific ...
Brys, Adam K, Sheth, Milan R, Sohn, David D, Sweidan, Alexander J   +3 more
core   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source

[Systemic mastocytosis].

Medicina cutanea ibero-latino-americana, 1989
213
Almagro Sanchez, M., Fonseca Capdevila, E., Sanchez Gil, A., Casado Jimenez, M., Jimenez Acosta, F.   +4 more
openaire   +4 more sources

Molecular quantification of tissue disease burden is a new biomarker and independent predictor of survival in mastocytosis

Haematologica, 2020
A high allele burden of the KIT D816V mutation in peripheral blood or bone marrow aspirates indicates multi-lineage hematopoietic involvement and has been associated with an aggressive clinical course of systemic mastocytosis.
Georg Greiner, Michael Gurbisz, Franz Ratzinger, Nadine Witzeneder, Svenja Verena Class, Gregor Eisenwort, Ingrid Simonitsch-Klupp, Harald Esterbauer, Matthias Mayerhofer, Leonhard Müllauer, Wolfgang R. Sperr, Peter Valent, Gregor Hoermann   +12 more
doaj   +1 more source

Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway [PDF]

, 2018
Mutations in KIT and TET2 are associated with myeloid malignancies. We show that loss of TET2-induced PI3K activation and -increased proliferation is rescued by targeting the p110α/δ subunits of PI3K.
Gerbaulet, A, Janga, SC, Kapur, R, Mali, RS, Paczesny, S, Palam, LR, Ramdas, B, Roers, A, Srivatsan, SN, Takemoto, CM, Tiu, RV, Vanhaesebroeck, B, Visconte, V, Xu, M   +13 more
core   +1 more source

Validation of the German version of Infants and Toddlers Dermatology Quality of Life (InToDermQoL) Questionnaire

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Skin diseases can greatly impair quality of life (QoL) of pediatric patients and their families. The Infants and Toddlers Dermatology Quality of Life questionnaire (InToDermQoL) is the first skin‐generic instrument assessing QoL in children ≤ 4 years, as reported by their caregiver. This study aimed to psychometrically
Juliane Traxler, Neuza da Silva Burger, Matthias Augustin, Hagen Ott, Sanna Hoffmann, Regina Fölster‐Holst, Maria Baumeister, Petra Staubach, Rachel Sommer   +8 more
wiley   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

Allergen-specific immunotherapy of Hymenoptera venom allergy:also a matter of diagnosis [PDF]

, 2015
Stings of hymenoptera can induce IgE-mediated hypersensitivity reactions in venom-allergic patients, ranging from local up to severe systemic reactions and even fatal anaphylaxis.
Schiener, Maximilian, Graessel, Anke, Ollert, Markus, Schmidt-Weber, Carsten B, Blank, Simon   +4 more
core   +2 more sources