Results 101 to 110 of about 2,603,502 (346)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

The five investor camps that try to beat the stock market

open access: yesBorsa Istanbul Review, 2020
This paper categorizes investors into five groups. They are: efficient markets, risk premium, genius superior traders, rejectors of efficient market theory and those who use research to make superior risk adjusted returns.
William T. Ziemba
doaj  

Systemic risk in a network fragility model analyzed with probability density evolution of persistent random walks [PDF]

open access: yes, 2007
We study the mean field approximation of a recent model of cascades on networks relevant to the investigation of systemic risk control in financial networks.
Battiston, Stefano, Lorenz, Jan
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Research on Remote-Sensing Identification Method of Typical Disaster-Bearing Body Based on Deep Learning and Spatial Constraint Strategy

open access: yesRemote Sensing
The census and management of hazard-bearing entities, along with the integrity of data quality, form crucial foundations for disaster risk assessment and zoning.
Lei Wang   +7 more
doaj   +1 more source

A comprehensive review of artificial intelligence methods and applications in skin cancer diagnosis and treatment: Emerging trends and challenges

open access: yesHealthcare Analytics, 2023
A substantial body of research has been published on artificial intelligence applications in skin cancer influenced by the latter's rising rates, the scarcity of specialized healthcare professionals, and rapid advancements in automated diagnosis and ...
Eman Rezk   +3 more
doaj  

Research on the Stability of the Banking System With Shadow Banking Under Macroeconomic Fluctuation

open access: yesFrontiers in Physics, 2020
In recent years, shadow banking is considered to be one of the important factors that cause the financial crisis and destroy the stability of the banking system.
Hongjie Pan, Hong Fan
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Systemic risk across sectors; Are banks different? [PDF]

open access: yes
This research compares systemic risk in the banking sector, the insurance sector, the construction sector, and the food sector. To measure systemic risk, we use extreme negative returns in stock market data for a time-varying panel of the 20 largest U.S.
Michiel Bijlsma, Sander Muns
core  

Fund Management and Systemic Risk - Lessons from the Global Financial Crisis [PDF]

open access: yes, 2013
Fund managers play an important role in increasing efficiency and stability in financial markets. But research also indicates that fund management in certain circumstances may contribute to the buildup of systemic risk and severity of financial crises ...
Allen   +78 more
core   +2 more sources

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