Results 111 to 120 of about 2,603,502 (346)
Interplay of integrins and selectins in metastasis
Molecular Oncology, EarlyView.Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva +2 more
wiley +1 more source
The Leaders, the Laggers, and the “Vulnerables”
Risks, 2020 We examine the lead-lag effect between the large and the small capitalization financial institutions by constructing two global weekly rebalanced indices.
Veni Arakelian, Shatha Qamhieh Hashem
doaj +1 more source
Systemic Risk: Conditional Distortion Risk Measures [PDF]
arXiv, 2019 In this paper, we introduce the rich classes of conditional distortion (CoD) risk measures and distortion risk contribution ($\Delta$CoD) measures as measures of systemic risk and analyze their properties and representations. The classes include the well-known conditional Value-at-Risk, conditional Expected Shortfall, and risk contribution measures in ...
arxiv
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Molecular Oncology, EarlyView.Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Redai diliTyphoons and their associated disaster chains pose serious threats to the lives and property of coastal residents, and they remain a focal point for research and response.
Zhou Ziying +4 more
doaj +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Multi-hazard direct economic loss risk assessment on the Tibet Plateau
Geomatics, Natural Hazards & RiskNatural disasters are becoming increasingly regional, frequent, and complex. Semi-quantitative risk assessments based on risk indices or relative risk levels lack quantitative parameters to characterize losses adequately.
Ru Ya +4 more
doaj +1 more source
Toward a framework for systemic multi-hazard and multi-risk assessment and management
iScience, 2023 Summary: In our increasingly interconnected world, natural hazards and their impacts spread across geographical, administrative, and sectoral boundaries.
Stefan Hochrainer-Stigler +10 more
doaj
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source