Results 1 to 10 of about 706,908 (282)
Antiphospholipid Antibodies and Systemic Scleroderma
Objective: Antiphospholipid antibodies (APLs) could be associated with an increased risk of vascular pathologies in systemic scleroderma. The aim of our study was to search for APLs in patients affected by systemic scleroderma and to evaluate their ...
Awa Oumar Touré+8 more
doaj +7 more sources
Uncommon skeletal findings in systemic sclerosis (scleroderma)
Scleroderma or progressive systemic sclerosis is a diffuse disease characterised by excessive deposition of collagen and small-vessel arteritis. Systemic sclerosis is divided into two groups. 1.
Betsie van der Walt+2 more
doaj +3 more sources
Systemic sclerosis is a profibrotic autoimmune disease mediated by the dysregulation of extracellular matrix synthesis. Formyl peptide receptor 2 (Fpr2) is a G protein-coupled receptor that modulates inflammation and host defense by regulating the ...
Gyu Tae Park, Tae Wook Lee
exaly +3 more sources
Background The study of molecular mechanisms characterizing disease progression may be relevant to get insights into systemic sclerosis (SSc) pathogenesis and to intercept patients at very early stage.
Chiara Bellocchi+6 more
doaj +1 more source
Fibrosing arthropathy in juvenile scleroderma
The group of scleroderma diseases includes a number of clinical entities, the main symptom of which is skin tightening. Scleroderma is a prominent example of these diseases, characterized by excessive synthesis and deposition of collagen in organs and ...
D. A. Dibrov+2 more
doaj +1 more source
Localized scleroderma: clinical spectrum and therapeutic update [PDF]
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis ...
Mariana Figueiroa Careta, Ricardo Romiti
doaj +2 more sources
We investigated 85 patients on the relationship between the axon reflex sweat volume or the reaction time and Raynaud's phenomenon, skin symptoms and patient background. Most patients did not show a decrease in sweating, but one in three patients showed less sweating in summer than in winter.
Miwa Ashida+5 more
wiley +1 more source
Renal Involvement in Systemic Sclerosis: An Update
Background: Systemic sclerosis is an immune-mediated rheumatic disease characterized by vascular abnormalities, tissue fibrosis and autoimmune phenomena.
Magdalena Chrabaszcz+6 more
doaj +1 more source
Classically described in the group of non‐cirrhotic portal hypertension, obliterative portal venopathy (OPV) causes are still unknown. Our aim is to describe the characteristics of 43 OPV patients and potential risk factors. Clinically significant portal hypertension was found in 28% of cases. The most frequent indication for liver biopsy was elevation
Vinícius Nunes+7 more
wiley +1 more source
Background Systemic sclerosis is an autoimmune multisystem disorder which affects the patients’ physical and psychological functioning. Scleroderma health assessment questionnaire used to measure physical disability in systemic sclerosis patients.
Samah Mahmoud Alian+3 more
doaj +1 more source