Results 11 to 20 of about 1,212,027 (321)

Brief Report: Smoking in Systemic Sclerosis: A Longitudinal European Scleroderma Trials and Research Group Study [PDF]

Arthritis & Rheumatology, 2018
Data on the role of tobacco exposure in systemic sclerosis (SSc; scleroderma) severity and progression are scarce. We aimed to assess the effects of smoking on the evolution of pulmonary and skin manifestations, based on the European Scleroderma Trials ...
V. Jaeger, G. Valentini, E. Hachulla, F. Cozzi, O. Distler, P. Airó, L. Czirják, Y. Allanore, E. Siegert, E. Rosato, M. Matucci-Cerinic, C. Caimmi, J. Henes, P. Carreira, V. Smith, F. del Galdo, C. Denton, S. Ullman, E. De Langhe, V. Riccieri, J. Alegre-Sancho, S. Rednic, U. Müller-Ladner, U. Walker   +23 more
semanticscholar   +7 more sources

Prognostic Significance of Raynaud's Phenomenon and Other Clinical Characteristics of Systemic Scleroderma [PDF]

Circulation, 1960
Richard G. Farmer, Ray W. Gifford, Edgar A. Hines   +2 more
openalex   +2 more sources

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Abraham, D, Ahmed-Abdi, B, Denton, C, Lafyatis, R, Layne, MD, Nikitorowicz-Buniak, J, Ponticos, M, Shiwen, X, Smith, BD, Stratton, R, Suki, B, Takahashi, A   +11 more
core   +28 more sources

Proteomic aptamer analysis reveals serum markers that characterize preclinical systemic sclerosis (SSc) patients at risk for progression toward definite SSc

Arthritis Research & Therapy, 2023
Background The study of molecular mechanisms characterizing disease progression may be relevant to get insights into systemic sclerosis (SSc) pathogenesis and to intercept patients at very early stage.
Chiara Bellocchi, Shervin Assassi, Marka Lyons, Maurizio Marchini, Chandra Mohan, Alessandro Santaniello, Lorenzo Beretta   +6 more
doaj   +1 more source

Fibrosing arthropathy in juvenile scleroderma

Современная ревматология, 2021
The group of scleroderma diseases includes a number of clinical entities, the main symptom of which is skin tightening. Scleroderma is a prominent example of these diseases, characterized by excessive synthesis and deposition of collagen in organs and ...
D. A. Dibrov, M. N. Starovoitova, O. V. Desinova   +2 more
doaj   +1 more source

Localized scleroderma: clinical spectrum and therapeutic update [PDF]

Anais Brasileiros de Dermatologia, 2015
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis ...
Mariana Figueiroa Careta, Ricardo Romiti
doaj   +2 more sources

Definition of Naturally Processed Peptides Reveals Convergent Presentation of Autoantigenic Topoisomerase I Epitopes in Scleroderma. [PDF]

, 2020
ObjectiveAutoimmune responses to DNA topoisomerase I (topo I) are found in a subset of scleroderma patients who are at high risk for interstitial lung disease (ILD) and mortality.
Boin, Francesco, Cole, Robert N, Darrah, Erika, Fava, Andrea, Guhr, Tara, McMahan, Zsuzsanna H, O'Meally, Robert N, Shah, Ami A, Tiniakou, Eleni, Wigley, Fredrick M   +9 more
core   +1 more source

Renal Involvement in Systemic Sclerosis: An Update

Kidney & Blood Pressure Research, 2020
Background: Systemic sclerosis is an immune-mediated rheumatic disease characterized by vascular abnormalities, tissue fibrosis and autoimmune phenomena.
Magdalena Chrabaszcz, Jolanta Małyszko, Mariusz Sikora, Rosanna Alda-Malicka, Anna Stochmal, Joanna Matuszkiewicz-Rowinska, Lidia Rudnicka   +6 more
doaj   +1 more source

Cultural adaptation and validation of the scleroderma health assessment questionnaire into Arabic language

Egyptian Rheumatology and Rehabilitation, 2023
Background Systemic sclerosis is an autoimmune multisystem disorder which affects the patients’ physical and psychological functioning. Scleroderma health assessment questionnaire used to measure physical disability in systemic sclerosis patients.
Samah Mahmoud Alian, Enass Abdel-kader Eliwa, Sohair Atia Ahmed, Manar Ibrahim Abd El-Fattah Ibrahim   +3 more
doaj   +1 more source

Preliminary safety and efficacy profile of prucalopride in the treatment of systemic sclerosis (SSc)-related intestinal involvement: results from the open label cross-over PROGASS study

Arthritis Research & Therapy, 2017
Background Prokinetics are used to treat enteric dismotility symptoms in systemic sclerosis (SSc) patients, but they often lack adequate efficacy. The most effective prokinetics belonging to the serotonin (5-HT4) receptor agonists class were withdrawn ...
Barbara Vigone, Monica Caronni, Adriana Severino, Chiara Bellocchi, Anna Rita Baldassarri, Mirella Fraquelli, Gaia Montanelli, Alessandro Santaniello, Lorenzo Beretta   +8 more
doaj   +1 more source