Results 61 to 70 of about 2,931,663 (352)

Depression in systemic sclerosis: Review of the neuro-immunologic link and pharmacological management

Medical Journal of Dr. D.Y. Patil University, 2016
Depression is a common neuropsychiatric condition associated with systemic sclerosis. The association of depression and systemic sclerosis is the result of multiple mechanisms such as autoimmune, significant morbidity due to multi-system involvement ...
Aditya Somani, Sujita Kumar Kar, Jyoti Ranjan Parida   +2 more
doaj   +1 more source

French recommendations for the management of systemic sclerosis

Orphanet Journal of Rare Diseases, 2021
Systemic sclerosis (SSc) is a generalized disease of the connective tissue, arterioles, and microvessels, characterized by the appearance of fibrosis and vascular obliteration.
E. Hachulla, C. Agard, Y. Allanore, J. Avouac, B. Bader-Meunier, A. Belot, A. Bérézné, A. Bouthors, G. Condette-Wojtasik, J. Constans, P. de Groote, É. Diot, F. Dumas, P. Jego, F. Joly, D. Launay, V. Le Guern, J. L. le Quintrec, G. Lescaille, C. Meune, B. Moulin, C. Nguyen, Nadine Omeish, F. Pène, M. Richard, J. Rochefort, A. Roren, O. Sitbon, V. Sobanski, M. Truchetet, L. Mouthon, M. Bayen, E. Bergot, S. Berthier, J. Bosco, Y. Bouhnik, B. Chaigne, V. Cottin, B. Crestani, C. Deligny, V. Descroix, D. Farge, D. Godard, B. Granel, P. Guilpain, B. Imbert, A. le Quellec, C. Lega, C. Lok, H. Maillard, T. Martin, G. Pugnet, V. Queyrel, L. Raffray, F. Rilliard, M. Romier, L. Schuller, A. Servettaz   +57 more
semanticscholar   +1 more source

Biomarkers in Systemic Sclerosis [PDF]

Biomarkers in Medicine, 2010
Systemic sclerosis is an autoimmune inflammatory disorder of unknown etiologycharacterized b y pronounced fibroproliferative alterations in the microvasculature, and frequent cellular and humoral immunity abnormalities, culminating in a severe and often progressive fibrotic process.
Castro, Susan V, Jimenez, Sergio A.
openaire   +2 more sources

Expansion of FCGR3A+ macrophages, FCN1+ mo-DC, and plasmacytoid dendritic cells associated with severe skin disease in systemic sclerosis.

Arthritis & Rheumatology, 2021
In this study, we sought a comprehensive understanding of myeloid cell types driving fibrosis in diffuse cutaneous systemic sclerosis (dcSSc) skin.
D. Xue, T. Tabib, C. Morse, Yi Yang, R. Domsic, D. Khanna, R. Lafyatis   +6 more
semanticscholar   +1 more source

Case report of systemic sclerosis: Uncommon manifestation of nephrotic syndrome post-renal crisis

SAGE Open Medical Case Reports, 2023
Kidney involvement in systemic sclerosis occurs in about 20% of cases, with scleroderma renal crisis as a significant complication. However, cases of glomerular disease with massive proteinuria are rare.
Ai Fujii, Takaya Kondo, Yasutaka Katsura, Sho Kumano, Serina Kita, Kazutoshi Nomura, Tomohisa Yabe, Norifumi Hayashi, Keiji Fujimoto, Hitoshi Yokoyama, Kengo Furuichi   +10 more
doaj   +1 more source

Quantification of mitochondrial DNA damage and copy number in circulating blood of patients with systemic sclerosis by a qPCR-based assay, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background: Although not fully understood, oxidative stress has been implicated in the pathogenesis of different autoimmune diseases such as systemic sclerosis.
Shafieh Movassaghi, Sara Jafari, Kowsar Falahati, Mitra Ataei, Mohammad Hossein Sanati, Zohreh Jadali   +5 more
doaj   +1 more source

Primary systemic sclerosis heart involvement: A systematic literature review and preliminary data-driven, consensus-based WSF/HFA definition

Journal of Scleroderma and Related Disorders, 2021
Introduction: Primary heart involvement in systemic sclerosis may cause morpho-functional and electrical cardiac abnormalities and is a common cause of death. The absence of a clear definition of primary heart involvement in systemic sclerosis limits our
C. Bruni, M. Buch, D. Furst, G. de Luca, A. Djokovic, R. Dumitru, A. Giollo, M. Polovina, A. Steelandt, Kostantinos Bratis, Y. Suliman, I. Milinković, A. Baritussio, Ghadeer Hasan, A. Xintarakou, Y. Isomura, G. Markousis-Mavrogenis, L. Tofani, S. Mavrogeni, L. Gargani, A. Caforio, C. Tschöpe, A. Ristic, K. Klingel, S. Plein, E. Behr, Y. Allanore, M. Kuwana, C. Denton, D. Khanna, T. Krieg, R. Marcolongo, I. Galetti, E. Zanatta, F. Tona, P. Seferović, M. Matucci-Cerinic   +36 more
semanticscholar   +1 more source

Single cell analysis in systemic sclerosis – A systematic review

Immunological Medicine
In recent years, rapid advances in research methods have made single cell analysis possible. Systemic sclerosis (SSc), a disease characterized by the triad of immune abnormalities, fibrosis, and vasculopathy, has also been the subject of various analyses.
Takemichi Fukasawa, Asako Yoshizaki-Ogawa, Atsushi Enomoto, Takashi Yamashita, Kiyoshi Miyagawa, Shinichi Sato, Ayumi Yoshizaki   +6 more
doaj   +1 more source

EULAR recommendations for the treatment of systemic sclerosis: 2023 update

Annals of the Rheumatic Diseases
Objectives To update the 2017 European Alliance of Associations for Rheumatology (EULAR) recommendations for treatment of systemic sclerosis (SSc), incorporating new evidence and therapies.
F. del Galdo, A. Lescoat, P. Conaghan, Eugenia Bertoldo, Jelena Čolić, Tânia Santiago, Y. Suliman, M. Matucci-Cerinic, A. Gabrielli, O. Distler, A. Hoffmann-Vold, I. Castellví, A. Balbir-Gurman, M. Vonk, L. Ananyeva, S. Rednic, A. Tarasova, P. Ostojic, V. Boyadzhieva, K. El Aoufy, Sue Farrington, I. Galetti, C. Denton, O. Kowal-Bielecka, U. Mueller-Ladner, Y. Allanore   +25 more
semanticscholar   +1 more source

Treatment of Systemic Sclerosis [PDF]

Rheumatic Disease Clinics of North America, 1989
Proper classification of patients into diffuse cutaneous and limited cutaneous subsets and the anticipation of complications are the keys to the management of individuals with systemic sclerosis (scleroderma). Patients with early diffuse disease and rapidly progressive skin thickening are at highest risk to develop serious internal organ involvement ...
openaire   +5 more sources