Results 81 to 90 of about 311,988 (356)

Docetaxel-Induced Systemic Sclerosis with Internal Organ Involvement Masquerading as Congestive Heart Failure

Case Reports in Immunology, 2017
Systemic sclerosis, or scleroderma, is a complex medical disorder characterized by limited or diffuse skin thickening with frequent involvement of internal organs such as lungs, gastrointestinal tract, or kidneys.
Bumsoo Park, Raghavendra C. Vemulapalli, Amit Gupta, Maria E. Shreve, Della A. Rees   +4 more
doaj   +1 more source

Angiogenic and angiostatic factors in renal scleroderma-associated vasculopathy [PDF]

, 2017
BACKGROUND: The angiogenesis in systemic sclerosis (SSc) is impaired. An imbalance of pro-angiogenic factors and angiogenesis inhibitors has been implicated in the progression of peripheral microvascular damage, defective vascular repair and fibrosis ...
Afeltra, Antonella M. Vittoria, Amoroso, Antonio, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Margiotta, Domenico, Navarini, Luca, Rosato, Edoardo   +7 more
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Interstitial lung disease in a patient with anti-eIF2B antibodies-positive systemic sclerosis: A case report and literature review

Respiratory Medicine Case Reports
We report the case of a 76-year-old male patient with systemic sclerosis positive for anti-eukaryotic initiation factor 2B (eIF2B) antibodies. He presented to our hospital with dyspnea on exertion and, following a comprehensive physical examination, was ...
Naoya Aoshiba, Kazutoshi Toriyama, Shohei Yamashita, Nao Shioiri, Yuko Iwata, Tomonori Uruma, Shinji Abe, Kenji Tsushima   +7 more
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. [PDF]

, 2016
OBJECTIVE: To examine whether lung endothelial cells (ECs) from patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) express mesenchymal cell-specific proteins and gene transcripts, indicative of the occurrence of endothelial-
Arciniegas, Beon, Cooley, Del Galdo, Falke, Gabrielli, Gilbane, Good, Goumans, Hashimoto, Herzog, Herzog, Hinz, Hinz, Humphreys, Jimenez, Katsumoto, Kendall, Kramann, Lamouille, LeBleu, Li, Li, Marelli-Berg, Matucci-Cerinic, McAnulty, Medici, Meeteren, Nolan, Pattanaik, Piera-Velazquez, Piera-Velazquez, Poslethwaite, Ranchoux, Rieder, Strieter, Varga, Veraldi, Wells, Yoshimatsu, Zeisberg, Zeisberg   +41 more
core   +2 more sources

AB0680 Psychological impact of autologous stem cell transplantation in systemic sclerosis patients and influence of support and coping strategies. | Annals of the Rheumatic Diseases [PDF]

, 2022
Marc Schmalzing, Nathalie Schwindl, Leona Zerhusen, J. Henes, A. C. Pecher, H. P. Tony, M. Gernert, A. Kuebler, Sonja Kleih-Dahms, P. Ziebell, M. Fröhlich   +10 more
openalex   +1 more source

Trends in Dermatopolymyositis Mortality, 1999–2022: A Nationwide Population‐Based Study, United States

Arthritis Care &Research, EarlyView.
We report the national burden of dermatopolymyositis mortality over the past quarter century using the US national vital statistics data. Age‐standardized mortality rates for dermatopolymyositis decreased at an annual rate of 3.8% each year, which was higher than the annual percent decrease for deaths from all other causes.
Elizabeth Matz, Ram R. Singh
wiley   +1 more source

Increased circulating levels of vitamin D binding protein in MS patients [PDF]

, 2015
Vitamin D (vitD) low status is currently considered a main environmental factor in multiple sclerosis (MS) etiology and pathogenesis. VitD and its metabolites are highly hydrophobic and circulate mostly bound to the vitamin D binding protein (DBP) and ...
Cortese, Antonio, Francisci, Silvia, Gauzzi, Maria Cristina, Gessani, Sandra, Mechelli, Rosella, Millefiorini, Enrico, Purificato, Cristina, Rinaldi, Arturo Ottavio, Salvetti, Marco, Sanseverino, Isabella   +9 more
core   +2 more sources

Treatment of Systemic Sclerosis [PDF]

Rheumatic Disease Clinics of North America, 1989
Proper classification of patients into diffuse cutaneous and limited cutaneous subsets and the anticipation of complications are the keys to the management of individuals with systemic sclerosis (scleroderma). Patients with early diffuse disease and rapidly progressive skin thickening are at highest risk to develop serious internal organ involvement ...
openaire   +5 more sources