Results 1 to 10 of about 74,985 (254)

Autoantibodies in systemic vasculitis [PDF]

Frontiers in Immunology, 2015
Systemic vasculitis is a heterogeneous group of disorders characterized by inflammation and necrosis in the vessel wall. The diagnosis of a systemic vasculitis is challenging, because patients usually present a broad spectrum of manifestations that vary according to the predominant size of vessels affected, organs and systems involved, and the extent ...
Alexandre Wagner Silva De Souza
doaj   +3 more sources

The modern therapy of systemic vasculitides: perspectives and challenges [PDF]

Терапевтический архив, 2018
Systemic vasculitis is a heterogeneous group of inflammatory diseases, which are classified according to the diameter of the affected vessels. The treatment of systemic vasculitis is no longer empirical, because of increasing number of randomized ...
P.I. NOVIKOV, A.S. ZYKOVA, S.V. MOISEEV
doaj   +2 more sources

Voclosporin and the Antiviral Effect Against SARS-CoV-2 in Immunocompromised Kidney Patients

Kidney International Reports, 2023
Introduction: Immunocompromised kidney patients are at increased risk of prolonged SARS-CoV-2 infection and related complications. Preclinical evidence demonstrates a more potent inhibitory effect of voclosporin on SARS-CoV-2 replication than tacrolimus ...
Eline J. Arends, Soufian Meziyerh, Dirk Jan A.R. Moes, Sylvia W.A. Kamerling, Sandra van der Kooy, Natacha S. Ogando, Eric J. Snijder, Martijn van Hemert, Leo G. Visser, Mariet C.W. Feltkamp, Eric C.J. Claas, Ton J. Rabelink, Cees van Kooten, Aiko P.J. de Vries, Y.K. Onno Teng   +14 more
doaj   +1 more source

Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial

Trials, 2022
Background Belimumab, an anti-B-cell activating factor antibody, is approved for the treatment of auto-antibody positive systemic lupus erythematosus with a high degree of disease activity.
Mieke van Schaik, Eline J. Arends, Darius Soonawala, Ellen van Ommen, Karina de Leeuw, Maarten Limper, Pieter van Paassen, Tom W. J. Huizinga, René E. M. Toes, Cees van Kooten, Joris I. Rotmans, Ton J. Rabelink, Y. K. Onno Teng   +12 more
doaj   +1 more source

Systemic Vasculitis

The International Journal of Lower Extremity Wounds, 2002
The systemic vasculitides are a heterogeneous group of disorders characterized by inflammation of blood vessel walls. They can be classified according to the size of vessel affected and also into primary de novo vasculitides and secondary to other disease processes. Treatments differ and overlap depending on the type of vasculitis.
Jordan, Kelsey M., Cooper, Cyrus
openaire   +4 more sources

Highly Sensitive Flow Cytometric Detection of Residual B-Cells After Rituximab in Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis Patients

Frontiers in Immunology, 2020
BackgroundB-cell depletion with rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients.
Laura S. van Dam, Jelle M. Oskam, Sylvia W. A. Kamerling, Eline J. Arends, O. W. Bredewold, Magdalena A. Berkowska, Jacques J. M. van Dongen, Ton J. Rabelink, Cees van Kooten, Y. K. Onno Teng   +9 more
doaj   +1 more source

The Impact of High Dose Glucocorticoids on Bone Health and Fracture Risk in Systemic Vasculitides

Frontiers in Endocrinology, 2022
Systemic vasculitides are a range of conditions characterized by inflammation of blood vessels which may manifest as single organ or life-threatening multisystem disease.
Christopher David Box, Owen Cronin, Owen Cronin, Barbara Hauser, Barbara Hauser   +4 more
doaj   +1 more source

Vasculitic peripheral neuropathy [PDF]

Reviews in Clinical Medicine, 2014
Primary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 % of patients have peripheral nervous system (PNS) involvement.
Mona Amini, Reza Boostani, Maryam Sahebari   +2 more
doaj   +3 more sources

Classification of systemic vasculitis: evolution from eponyms to modern criteria

Терапевтический архив, 2022
Systemic vasculitis is a manifold group of systemic autoimmune diseases characterized by the inflammation of the blood vessels. The first clinical cases of systemic vasculitis were described in the Middle Ages, and most of the currently recognised ...
Nikolay M. Bulanov, Pavel I. Novikov, Mariia A. Litvinova, Sergey V. Moiseev   +3 more
doaj   +1 more source

Neutrophil-to-lymphocyte ratio: A biomarker for predicting systemic involvement in iga vasculitis

Indian Journal of Rheumatology, 2020
Context:“IgA vasculitis, is an immune complex mediated, self limited cutaneous small vessel vasculitis, characterized by palpable purpurae, arthralgia or arthritis, gastrointestinal and/or renal involvement.” Systemic involvement is considered to be the ...
Rintu Merin George, Arun C Inamadar, Ajit B Janagond   +2 more
doaj   +1 more source