Results 141 to 150 of about 34,801,835 (296)

Systems analysis project advisory committee and MAPPS users group

, 1989
"October 20, 1989."Systems analysis: project 3471 / James D ...
Rushton, James D.
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Regulatory Bottlenecks Linking HDL Dysfunction, Inflammation, and Oxidative Stress: A Petri Net-Based Systems Analysis. [PDF]

Int J Mol Sci
Formanowicz D, Rynkiewicz AA, Formanowicz P.   +2 more
europepmc   +1 more source

Peak Analysis System [PDF]

Science, 1973
openaire   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Decoding disease and therapy through multiomics integration and systems analysis. [PDF]

Brief Bioinform
Mathew MJ, Mathew J, Chacko RM, Bayry J, Zagury JF.   +4 more
europepmc   +1 more source

Health system effects of economy-wide inflation: how resilient are European health systems?

25 p.This policy brief looks at the impacts of high economy-wide price growth on health systems and considers policy responses. The brief explores the limited literature on the topic and provides a framework for analysis.
Jeurissen, Patrick, den Besten, Marjon, European Observatory on Health Systems and Policies, Hasan, Rono, Cylus, Jonathan   +4 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Integrative systems analysis reveals heat-induced functional divergence in cultivated and wild tomato genotypes. [PDF]

BMC Plant Biol
Şimsek E, Yıldız K, Çevik S, Akbudak MA.   +3 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source