Results 161 to 170 of about 12,538,458 (271)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Author Correction: Quantifying both socioeconomic and climate uncertainty in coupled human-Earth systems analysis. [PDF]

Nat Commun
Morris J, Sokolov A, Reilly J, Libardoni A, Forest C, Paltsev S, Schlosser CA, Prinn R, Jacoby H.   +8 more
europepmc   +1 more source

Systems analysis of the effects of the 2014-16 Ebola crisis on WHO-reporting nations' policy adaptations and 2020-21 COVID-19 response: a systematized review. [PDF]

Global Health, 2023
Hanson-DeFusco J, Shi M, Du Z, Zounon O, Hounnouvi FM, DeFusco A.   +5 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Author Correction: An assessment of energy system transformation pathways to achieve net-zero carbon dioxide emissions in Switzerland

Communications Earth & Environment, 2023
Evangelos Panos, Ramachandran Kannan, Stefan Hirschberg, Tom Kober   +3 more
doaj   +1 more source

Who benefits from mobile health interventions? A dynamical systems analysis of psychological well-being in early adults. [PDF]

Appl Psychol Health Well Being
Heshmati S, Muth C, Li Y, Roeser RW, Smyth JM, Vandekerckhove J, Chow SM, Oravecz Z.   +7 more
europepmc   +1 more source

Editorial for the Special Issue on Micro/Nano Structures and Systems: Analysis, Design, Manufacturing, and Reliability. [PDF]

Micromachines (Basel), 2023
Georgantzinos SK.
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Changing temporal patterns in patient-reported wish to live and wish to die signal the imminent emergence and aftermath of suicide attempts: a dynamical systems analysis. [PDF]

BMC Psychiatry
Bryan CJ, Bozzay ML, Hay J, Starkey A, Tabares JV, Baker JC.   +5 more
europepmc   +1 more source

Racial disparities in access to health care infrastructure across US counties: A geographic information systems analysis. [PDF]

Front Public Health, 2023
Guo J, Dickson S, Berenbrok LA, Tang S, Essien UR, Hernandez I.   +5 more
europepmc   +1 more source