Results 11 to 20 of about 2,713,734 (236)
Resonance, 2010 Systems biology seeks to study biological systems as a whole, contrary to the reductionist approach that has dominated biology. Such a view of biological systems emanating from strong foundations of molecular level understanding of the individual components in terms of their form, function and interactions is promising to transform the level at which ...
Raman, Karthik, Chandra, Nagasuma
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Systems biology and cancer [PDF]
Progress in Biophysics and Molecular Biology, 2011 The systems approach to complex biological problems has rapidly gained ground during the first decade of this century. There are several reasons for this development. An important one is that while the achievement of sequencing the complete human genome, and those of other species, has been of great benefit to fundamental science, for example in ...
Soto, A +3 more
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Systems biology at the Institute for Systems Biology [PDF]
Briefings in Functional Genomics and Proteomics, 2008 Systems biology represents an experimental approach to biology that attempts to study biological systems in a holistic rather than an atomistic manner. Ideally this involves gathering dynamic and global data sets as well as phenotypic data from different levels of the biological information hierarchy, integrating them and modeling them graphically and ...
David J. Galas +3 more
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Systems biology reveals biology of systems [PDF]
Complexity, 2010 AbstractIn the last decades, genomic and postgenomic technologies obtained a great amount of information on molecular bases of cell physiology and organization. In spite of this, the knowledge of cells and living organisms in their entirety, is far from being achieved.
Alessandro Giuliani +2 more
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Frontiers in Genetics, 2015 The marine environment accounts for an important part of the earth biodiversity, featuring several types of (even extreme) ecosystems, and is at the origin of life. Marine prokaryotic and eukaryotic organisms are very diverse, and are sometimes, in particular for the latter, the result of intricate evolutionary history. This biodiversity, encounters in
Tonon, Thierry, Eveillard, Damien
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AutoAnalyze in Systems Biology [PDF]
Bioinformatics and Biology Insights, 2019 AutoAnalyze is a highly customizable framework for the visualization and analysis of large-scale model graphs. Originally developed for use in the automotive domain, it also supports efficient computation within molecular networks represented by reaction equations.
Jian Li +4 more
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Systems biology in animal sciences [PDF]
, 2011 Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Bannink, A. +4 more
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What is systems biology? [PDF]
Frontiers in Physiology, 2010 Systems biology is increasingly popular, but to many biologists it remains unclear what this new discipline actually encompasses. This brief personal perspective starts by outlining the asthetic qualities that motivate systems biologists, discusses which activities do not belong to the core of systems biology, and finally explores the crucial link with
Rainer Breitling, Rainer Breitling
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Computational Systems Biology [PDF]
The Scientific World Journal, 2013 The complex biological systems consist of distinct molecules that exert their functions by interacting with each other, which makes it a big challenge to understand how the cellular machinery works. Recently, the accumulation of a large amount of multiscale omics data, such as next-generation sequencing data and protein interaction data, provides ...
Weidong Tian +3 more
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Computational inference in systems biology [PDF]
, 2015 Parameter inference in mathematical models of biological pathways, expressed as coupled ordinary differential equations (ODEs), is a challenging problem. The computational costs associated with repeatedly solving the ODEs are often high.
A. Lotka +9 more
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