Results 11 to 20 of about 1,188,505 (261)
A metabolic regulatory network for the Caenorhabditis elegans intestine
iScience, 2022 Summary: Metabolic perturbations can affect gene expression, for instance to rewire metabolism. While numerous efforts have measured gene expression in response to individual metabolic perturbations, methods that determine all metabolic perturbations ...
Sushila Bhattacharya +7 more
doaj +1 more source
iScience, 2021 Summary: Whether arterial-venous differences of primary endothelial cells commonly used for vascular research are preserved in vitro remains under debate.
Fabian Vega-Tapia +2 more
doaj +1 more source
iScience, 2021 Summary: Base editing (BE) is a promising genome engineering tool for modifying DNA or RNA and has been widely used in various microorganisms as well as eukaryotic cells.
Tianyuan Su +6 more
doaj +1 more source
A yeast chemogenomic screen identifies pathways that modulate adipic acid toxicity
iScience, 2021 Summary: Adipic acid production by yeast fermentation is gaining attention as a renewable source of platform chemicals for making nylon products. However, adipic acid toxicity inhibits yeast growth and fermentation.
Eugene Fletcher +3 more
doaj +1 more source
STAR Protocols, 2023 Summary: RNA-binding proteins (RBPs) can bind and mediate RNA-RNA contacts. However, identifying specific RBP-organized RNA-RNA contacts remains challenging.
Rong Ye, Naijing Hu, Yuanchao Xue
doaj +1 more source
Planetary Systems Biology [PDF]
Molecular Cell, 2005 Combining paleogenetics, protein engineering, synthetic biology, and metabolic modeling, a planetary biology perspective is brought to bear on adaptive evolutionary events in ancient bacteria.
Department of Chemistry, University of Florida, Gainesville, FL 32611 USA ( host institution ) +2 more
openaire +3 more sources
Systems Biology in Periodontitis
Frontiers in Dental Medicine, 2022 Systems biology is a promising scientific discipline that allows an integrated investigation of host factors, microbial composition, biomarkers, immune response and inflammatory mediators in many conditions such as chronic diseases, cancer, neurological ...
Davi Neto de Araújo Silva +2 more
doaj +1 more source
Systems chemical biology [PDF]
Nature Chemical Biology, 2007 The increasing availability of data related to genes, proteins and their modulation by small molecules has provided a vast amount of biological information leading to the emergence of systems biology and the broad use of simulation tools for data analysis.
Oprea, Tudor I +3 more
openaire +2 more sources
Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning
iScience, 2021 Summary: Clear cell renal cell carcinoma (ccRCC) is the most common histological type of kidney cancer and has high heterogeneity. Stratification of ccRCC is important since distinct subtypes differ in prognosis and treatment.
Xiangyu Li +12 more
doaj +1 more source
Systems Biology, Integrative Biology, Predictive Biology [PDF]
Cell, 2005 The pursuit of science is based on empiricism enabled by advancing technologies. Theories then emerge that unify our understanding of natural order. The trinity of experimentation, theory, and technology that underlies the scientific method cannot be placed into a hierarchy of importance.
openaire +2 more sources