Results 21 to 30 of about 1,232,353 (260)
iScience, 2021 Summary: Genomic data can facilitate personalized treatment decisions by enabling therapeutic hypotheses in individual patients. Mutual exclusivity has been an empirically useful signal for identifying activating mutations that respond to single agent ...
Haider Inam +8 more
doaj +1 more source
Integrative biology and systems biology [PDF]
Molecular Systems Biology, 2005 Mol Syst Biol. 1: 2005.0004 Demarcations of scientific fields have always followed either a conceptual breakthrough or have been a result of profoundly enabling technologies. Quantum theory and quantum mechanics revolutionized physics and engineering, but high‐energy physics is a discipline fundamentally enabled by the linear accelerator.
openaire +2 more sources
Interfacing systems biology and synthetic biology [PDF]
Genome Biology, 2009 A report of BioSysBio 2009, the IET conference on Synthetic Biology, Systems Biology and Bioinformatics, Cambridge, UK, 23-25 March 2009.
Lister AL +5 more
openaire +3 more sources
iScience, 2023 Summary: The activation of IKK/NF-κB by genotoxic stress is a crucial process in the DNA damage response. Due to the anti-apoptotic impact of NF-κB, it can affect cell-fate decisions upon DNA damage and therefore interfere with tumor therapy-induced cell
Fabian Konrath +4 more
doaj +1 more source
Clinical Pharmacology & Therapeutics, 2010 In just over a decade, Systems Biology has moved from being an idea, or rather a disparate set of ideas, to a mainstream feature of research and funding priorities. Institutes, departments, and centers of various flavors of Systems Biology have sprung up all over the world. An Internet search now produces more than 2 million hits.
Kohl P. +3 more
openaire +4 more sources
Systems biology: The reincarnation of systems theory applied in biology? [PDF]
Briefings in Bioinformatics, 2001 With the availability of quantitative data on the transcriptome and proteome level, there is an increasing interest in formal mathematical models of gene expression and regulation. International conferences, research institutes and research groups concerned with systems biology have appeared in recent years and systems theory, the study of organisation
openaire +2 more sources
The Biology of the Interferon System [PDF]
Nature Biotechnology, 1983 info:eu-repo/semantics ...
openaire +3 more sources
Cells, 2013 Systems biology aims at achieving a system-level understanding of living organisms and applying this knowledge to various fields such as synthetic biology, metabolic engineering, and medicine. System-level understanding of living organisms can be derived
Bor-Sen Chen, Chia-Chou Wu
doaj +1 more source
Journal of Integrative Bioinformatics, 2022 Visual representations are commonly used to explore, analyse, and communicate information and knowledge in systems biology and beyond. Such visualisations not only need to be accurate but should also be aesthetically pleasing and informative.
Schreiber Falk, Czauderna Tobias
doaj +1 more source
Systems Biology, Integrative Biology, Predictive Biology [PDF]
Cell, 2005 The pursuit of science is based on empiricism enabled by advancing technologies. Theories then emerge that unify our understanding of natural order. The trinity of experimentation, theory, and technology that underlies the scientific method cannot be placed into a hierarchy of importance.
openaire +2 more sources