Results 21 to 30 of about 2,985,376 (297)
Computational inference in systems biology [PDF]
, 2015 Parameter inference in mathematical models of biological pathways, expressed as coupled ordinary differential equations (ODEs), is a challenging problem. The computational costs associated with repeatedly solving the ODEs are often high.
A. Lotka +9 more
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Engineering simulations for cancer systems biology [PDF]
, 2012 Computer simulation can be used to inform in vivo and in vitro experimentation, enabling rapid, low-cost hypothesis generation and directing experimental design in order to test those hypotheses.
Andrews, Paul S. +8 more
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Systems Biology in Periodontitis
Frontiers in Dental Medicine, 2022 Systems biology is a promising scientific discipline that allows an integrated investigation of host factors, microbial composition, biomarkers, immune response and inflammatory mediators in many conditions such as chronic diseases, cancer, neurological ...
Davi Neto de Araújo Silva +2 more
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Stochastic Physics, Complex Systems and Biology [PDF]
, 2012 In complex systems, the interplay between nonlinear and stochastic dynamics, e.g., J. Monod's necessity and chance, gives rise to an evolutionary process in Darwinian sense, in terms of discrete jumps among attractors, with punctuated equilibrium ...
A Lasota +45 more
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iScience, 2023 Summary: The activation of IKK/NF-κB by genotoxic stress is a crucial process in the DNA damage response. Due to the anti-apoptotic impact of NF-κB, it can affect cell-fate decisions upon DNA damage and therefore interfere with tumor therapy-induced cell
Fabian Konrath +4 more
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Mechanical and Systems Biology of Cancer [PDF]
, 2018 Mechanics and biochemical signaling are both often deregulated in cancer, leading to cancer cell phenotypes that exhibit increased invasiveness, proliferation, and survival.
Bakal, Chris +2 more
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Integrative biology and systems biology [PDF]
Molecular Systems Biology, 2005 Mol Syst Biol. 1: 2005.0004 Demarcations of scientific fields have always followed either a conceptual breakthrough or have been a result of profoundly enabling technologies. Quantum theory and quantum mechanics revolutionized physics and engineering, but high‐energy physics is a discipline fundamentally enabled by the linear accelerator.
openaire +2 more sources
Interfacing systems biology and synthetic biology [PDF]
Genome Biology, 2009 A report of BioSysBio 2009, the IET conference on Synthetic Biology, Systems Biology and Bioinformatics, Cambridge, UK, 23-25 March 2009.
Lister AL +5 more
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iScience, 2021 Summary: Genomic data can facilitate personalized treatment decisions by enabling therapeutic hypotheses in individual patients. Mutual exclusivity has been an empirically useful signal for identifying activating mutations that respond to single agent ...
Haider Inam +8 more
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Enhanced Operational Semantics in Systems Biology [PDF]
, 2003 We are faced with a great challenge: the cross-fertilization between the fields of formal methods for concurrency, in the computer science domain, and systems biology in the biological ...
A. Dovier +11 more
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