Results 11 to 20 of about 11,342,017 (299)
AutoAnalyze in Systems Biology [PDF]
Bioinformatics and Biology Insights, 2019 AutoAnalyze is a highly customizable framework for the visualization and analysis of large-scale model graphs. Originally developed for use in the automotive domain, it also supports efficient computation within molecular networks represented by reaction equations. A static analysis approach is used for efficient treatment-condition-specific simulation.
Saad, Christian +3 more
openaire +5 more sources
iScience, 2021 Summary: Hypoxia is a critical factor in solid tumors that has been associated with cancer progression and aggressiveness. We recently developed a hypoxia fate mapping system to trace post-hypoxic cells within a tumor for the first time.
Heber L. Rocha +7 more
doaj +1 more source
Pioneer factors in development and cancer
iScience, 2021 Summary: Transcription factors (TFs) are essential mediators of epigenetic regulation and modifiers of penetrance. Studies from the past decades have revealed a sub-class of TF that is capable of remodeling closed chromatin states through targeting ...
Benjamin D. Sunkel, Benjamin Z. Stanton
doaj +1 more source
iScience, 2021 Summary: We aimed to identify triple-negative breast cancer (TNBC) drivers that regulate survival time as predictive signatures that improve TNBC prognostication.
Courtney D. Dill +4 more
doaj +1 more source
So what do we really mean when we say that systems biology is holistic? [PDF]
, 2010 Background: An old debate has undergone a resurgence in systems biology: that of reductionism versus holism. At least 35 articles in the systems biology literature since 2003 have touched on this issue.
Gatherer, Derek
core +5 more sources
iScience, 2022 Summary: Autoimmune diseases (ADs) are at a significantly higher risk of cancers with unclear mechanism. By searching GWAS catalog database and Medline, susceptible genes for five common ADs, including systemic lupus erythematosus (SLE), rheumatoid ...
Shasha Li +10 more
doaj +1 more source
A metabolic regulatory network for the Caenorhabditis elegans intestine
iScience, 2022 Summary: Metabolic perturbations can affect gene expression, for instance to rewire metabolism. While numerous efforts have measured gene expression in response to individual metabolic perturbations, methods that determine all metabolic perturbations ...
Sushila Bhattacharya +7 more
doaj +1 more source
iScience, 2021 Summary: Whether arterial-venous differences of primary endothelial cells commonly used for vascular research are preserved in vitro remains under debate.
Fabian Vega-Tapia +2 more
doaj +1 more source
applied-systems-biology/mcat: Mcat v1.0.0
, 2021 This is the first release of the MSOT cluster analysis toolkit (Mcat) as ImageJ plugin, accompanied by its user manual and example data. Installation If you don't have ImageJ/Fiji installed yet, you can get it from https://imagej.net/Fiji.
Applied Systems Biology, Bianca Hoffmann
core +1 more source