Results 41 to 50 of about 11,342,017 (299)
An oscillating reaction network with an exact closed form solution in the time domain
BMC Bioinformatics, 2023 Background Oscillatory behavior is critical to many life sustaining processes such as cell cycles, circadian rhythms, and notch signaling. Important biological functions depend on the characteristics of these oscillations (hereafter, oscillation ...
Joseph Hellerstein
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Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas
iScience, 2021 Summary: Deconstructing tissue-specific effects of genes and variants on proliferation is critical to understanding cellular transformation and systematically selecting cancer therapeutics.
Udit Parekh +8 more
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Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
Small RNA biology is systems biology
BMB Reports, 2011 During the last decade small regulatory RNA (srRNA) emerged as central players in the regulation of gene expression in all kingdoms of life. Multiple pathways for srRNA biogenesis and diverse mechanisms of gene regulation may indicate that srRNA regulation evolved independently multiple times.
Jost, Daniel +2 more
openaire +4 more sources
Frontiers in Physiology, 2010 Systems biology is increasingly popular, but to many biologists it remains unclear what this new discipline actually encompasses. This brief personal perspective starts by outlining the aesthetic qualities that motivate systems biologists, discusses ...
Rainer Breitling, Rainer Breitling
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Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells
iScience, 2021 Summary: Many players regulating the CD4+ T cell-mediated inflammatory response have already been identified. However, the critical nodes that constitute the regulatory and signaling networks underlying CD4 T cell responses are still missing.
Christophe M. Capelle +6 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin +11 more
wiley +1 more source
Systems Biology and Physiome Projects
, 2009 The emergence of systems biology as a result of the molecular revolution in biology and progress in genomic and proteomics is now beginning to affect medicine. ..
Popel, AS, Hunter, Peter
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Cloning of DNA oligo pools for in vitro expression
STAR Protocols, 2022 Summary: Oligo library pools are powerful tools for systematic investigation of genetic and transcriptomic machinery such as promoter function and gene regulation, non-coding RNAs, or RNA modifications.
Anna Uzonyi, Ronit Nir, Schraga Schwartz
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