Results 51 to 60 of about 12,579,596 (265)

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Perturbation of Interaction Networks for Application to Cancer Therapy

Cancer Informatics, 2007
We present a computational approach for studying the effect of potential drug combinations on the protein networks associated with tumor cells.
Steven J. M. Jones, Asim S. Siddiqui, Adrian P. Quayle   +2 more
doaj  

SCLC TumorMiner: A genomics platform for small cell lung cancer precision oncology

iScience
Summary: Small cell lung cancer (SCLC) is among the most aggressive malignancies. Unlike many other cancers, it is not represented in The Cancer Genome Atlas, and available datasets are fragmented across institutions, disease stages, and treatment ...
Fathi Elloumi, Anjali Dhall, Daiki Taniyama, Augustin Luna, Yasuhiro Arakawa, Sudhir Varma, Yanghsin Wang, Anisha Tehim, Mark Raffeld, Kenneth Aldape, Christophe Redon, Roshan Shrestha, William Reinhold, Mirit Aladjem, Jaydira Del Rivero, Nitin Roper, Anish Thomas, Yves Pommier   +17 more
doaj   +1 more source

Development of OX40 agonists for canine cancer immunotherapy

iScience, 2022
Summary: Recent breakthroughs in cancer immunotherapy have provided unprecedented clinical benefits to human cancer patients. Cancer is also one of the most common causes of death in pet dogs.
Damien Ruiz, Chloe Haynes, Jonathan Marable, Chetan Pundkar, Rebecca L. Nance, Deepa Bedi, Payal Agarwal, Amol S. Suryawanshi, Amarjit Mishra, Bruce F. Smith, Maninder Sandey   +10 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Exploratory Visual Analysis of Statistical Results from Microarray Experiments Comparing High and Low Grade Glioma

Cancer Informatics, 2007
The biological interpretation of gene expression microarray results is a daunting challenge. For complex diseases such as cancer, wherein the body of published research is extensive, the incorporation of expert knowledge provides a useful analytical ...
Jason H. Moore, Mark A. Israel, David M. Reif   +2 more
doaj  

Logical and experimental modeling of cytokine and eicosanoid signaling in psoriatic keratinocytes

iScience, 2021
Summary: Psoriasis is a chronic skin disease, in which immune cells and keratinocytes keep each other in a state of inflammation. It is believed that phospholipase A2 (PLA2)-dependent eicosanoid release plays a key role in this.
Eirini Tsirvouli, Felicity Ashcroft, Berit Johansen, Martin Kuiper   +3 more
doaj   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

VARIABILITY IN SENSORY ECOLOGY: EXPANDING THE BRIDGE BETWEEN PHYSIOLOGY AND EVOLUTIONARY BIOLOGY [PDF]

, 2009
International audienceSensory organs represent the interface between the central nervous system of organisms and the environment in which they live.
Irschick, Duncan, Lars Chittka, Dangles, O, Chittka, Lars, Irschick, D, Chittka, L, Olivier Dangles, Duncan Irschick, Casas, J, Dangles, Olivier, Casas, Jérome, Jérôme Casas   +11 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source