Results 31 to 40 of about 25,134,561 (338)

Selected issues of systems engineering methodology in the design of transport systems

Transport Technologies, 2022
The selected issues of system engineering methodology in the design of transport systems have been presented. The discussed methodological issues were presented in the example of the metropolitan railway concept project.
Grzegorz Karoń, Ryszard Janecki, Jerzy Mikulski   +2 more
doaj   +1 more source

Towards a Unified Modeling and Simulation Framework for Space Systems: Integrating Model-Based Systems Engineering with Open Source Multi-Domain Simulation Environments

Aerospace
The increasing complexity of modern space systems requires a more integrated and scalable approach to their design, analysis, and verification. Model-Based Systems Engineering (MBSE) has emerged as a powerful methodology for managing the complexity of ...
Serena Campioli, Giacomo Luccisano, Davide Ferretto, Fabrizio Stesina   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Optimization of industrial symbiosis in coffee-based eco-industrial park design [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: The coffee agroindustry in Indonesia plays a significant economic role as the third largest coffee producer worldwide. Despite the high economic contribution, the coffee agroindustry also raises environmental issues along its ...
N. Laili, T. Djatna, N.S. Indrasti, M. Yani   +3 more
doaj   +1 more source

FUNDAMENTAL KNOWLEDGE AND FLEXIBILITY OF THINKING AS PRIORITIES OF MANAGEMENT EDUCATION FOR TECHNOLOGICAL BREAKTHROUGH

Стратегические решения и риск-менеджмент, 2022
The article substantiates the need for a radical review of approaches to the training of managers in high technological industries, whose professional activity context is defined by continuous crises, growing uncertainty, dynamic trends, the massive ...
L. D. Gitelman, A. P. Isayev, M. V. Kozhevnikov, T. B. Gavrilova   +3 more
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Transdisciplinary systems engineering: implications, challenges and research agenda

International Journal of Agile Systems and Management, 2019
Transdisciplinary processes have been the subject of research since several decades already. Transdisciplinary processes are aimed at solving ill-defined and socially relevant problems.
N. Wognum, C. Bil, F. Elgh, M. Peruzzini, J. Stjepandić, W. Verhagen   +5 more
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Exhaustive Description of the System Architecture and Prototype Implementation of an IoT-Based eHealth Biometric Monitoring System for Elders in Independent Living

Sensors, 2021
In this paper, we present an exhaustive description of an extensible e-Health Internet-connected embedded system, which allows the measurement of three biometric parameters: pulse rate, oxygen saturation and temperature, via several wired and wireless ...
Cristian Vizitiu, Călin Bîră, Adrian Dinculescu, Alexandru Nistorescu, Mihaela Marin   +4 more
doaj   +1 more source