Results 71 to 80 of about 4,736,102 (330)

Engineering complex systems [PDF]

open access: yesNature, 2004
The emergent properties of complex systems are far removed from the traditional preoccupation of engineers with design and purpose.
openaire   +3 more sources

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Development of an automated guided vehicle controller using a systems engineering approach

open access: yesSouth African Journal of Industrial Engineering, 2016
Automated guided vehicles (AGVs) are widely used for transporting materials in industry and commerce. In this research, an intelligent AGV-based material-handling system was developed using a model- based systems engineering (MBSE) approach.
Ferreira, Tremaine, Gorlach, Igor
doaj   +1 more source

Ground-state Stabilization of Open Quantum Systems by Dissipation

open access: yes, 2015
Control by dissipation, or environment engineering, constitutes an important methodology within quantum coherent control which was proposed to improve the robustness and scalability of quantum control systems.
James, Matthew R.   +2 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Embedded Master’s Students Conduct Highly Relevant Research Using Industry as Their Laboratory

open access: yesTechnology Innovation Management Review, 2019
This article analyzes participatory action research conducted by Systems Engineering master’s students embedded fifty percent in industrial companies for three years.
Kristin Falk, Gerrit Muller
doaj   +1 more source

OntoEng: A design method for ontology engineering in information systems [PDF]

open access: yes, 2009
This paper addresses the design problem relating to ontology engineering in the discipline of information systems. Ontology engineering is a realm that covers issues related to ontology development and use throughout its life span.
Al-Debei, MM, Fitzgerald, G
core  

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Algebraic Expressions for Complex Deep Learning Systems Modeling and Analysis

open access: yesIEEE Access
Many modern Deep Learning (DL) systems have achieved impressive state-of-the-art results by combining individual sub-systems, including foundation models, to form increasingly more complex DL systems.
Rhandall Valdez-Yepez   +3 more
doaj   +1 more source

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