Results 71 to 80 of about 4,654,755 (329)

OntoEng: A design method for ontology engineering in information systems [PDF]

open access: yes, 2009
This paper addresses the design problem relating to ontology engineering in the discipline of information systems. Ontology engineering is a realm that covers issues related to ontology development and use throughout its life span.
Al-Debei, MM, Fitzgerald, G
core  

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Engineering Systems with Standards and Digital Models: Development of a 15288-SysML Grid

open access: yesSystems
The paradigm shift that has spurred the fourth industrial revolution, in what is termed Industry 4.0, has ushered in the need to adopt digital technologies throughout the worldwide industrial base to support system design efforts. The adoption of digital
Kevin MacG. Adams   +2 more
doaj   +1 more source

Embedded Master’s Students Conduct Highly Relevant Research Using Industry as Their Laboratory

open access: yesTechnology Innovation Management Review, 2019
This article analyzes participatory action research conducted by Systems Engineering master’s students embedded fifty percent in industrial companies for three years.
Kristin Falk, Gerrit Muller
doaj   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Agent Based Approaches to Engineering Autonomous Space Software

open access: yes, 2010
Current approaches to the engineering of space software such as satellite control systems are based around the development of feedback controllers using packages such as MatLab's Simulink toolbox.
Dennis, Louise A.   +4 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Engineering complex systems [PDF]

open access: yesNature, 2004
The emergent properties of complex systems are far removed from the traditional preoccupation of engineers with design and purpose.
openaire   +3 more sources

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

A Systems Engineering Approach to Physical Security of Oil & Gas Installations

open access: yesInternational Journal of Coastal and Offshore Engineering, 2019
A fundamental challenge facing security professionals is preventing loss; be that asset, production, or third-party losses. This is not dissimilar to what safety professionals have to face.
Sirous Yasseri
doaj  

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