Results 71 to 80 of about 3,975,199 (305)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The effects of interoperable information technology networks on patient safety: a realist synthesis

Health Services and Delivery Research, 2020
Background: Interoperable networks connect information technology systems of different organisations, allowing professionals in one organisation to access patient data held in another one.
Justin Keen, Maysam Abdulwahid, Natalie King, Judy Wright, Rebecca Randell, Peter Gardner, Justin Waring, Roberta Longo, Silviya Nikolova, Claire Sloan, Joanne Greenhalgh   +10 more
doaj   +1 more source

Quality-aware model-driven service engineering [PDF]

, 2008
Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Barrett, Ronan, Boskovic, Marko, Hasselbring, Wilhelm, Pahl, Claus   +3 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Restructuring Non-teaching Hospitals into Teaching Hospitals in Iran: Component Change in General Hospitals [PDF]

Journal of Qualitative Research in Health Sciences
Background: The present study investigated how a general hospital is restructured in Iran when transforming from a non-teaching into a teaching hospital.Methods: This applied study was conducted based on a mixed-method design from 2020 to 2021 using a ...
Niusha Shahidi Sadeghi, Mohammadreza Maleki, Soudabeh Vatankhah, Bahram Mohaghegh, Seyed Jafar Ehsanzadehsorati   +4 more
doaj   +1 more source

Integrity management systems

Recent years have seen various attempts at conceptualising integrity management within organisations. This chapter focuses on those integrity management models that take a systems approach. This emphasises interconnectedness and requisite variety, as well as the processual and iterative nature of integrity management and the importance of grassroots ...
Maesschalck, Jeroen, Hoekstra, Alain, van Montfort, André   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The integral system.

Central European journal of urology, 2011
The Integral System is a total care management system based on the Integral Theory which states 'prolapse and symptoms of urinary stress, urge, abnormal bowel & bladder emptying, and some forms of pelvic pain, mainly arise, for different reasons, from laxity in the vagina or its supporting ligaments, a result of altered connective tissue'.The organs ...
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source