Results 91 to 100 of about 779,188 (287)

Emergent complex neural dynamics

, 2010
A large repertoire of spatiotemporal activity patterns in the brain is the basis for adaptive behaviour. Understanding the mechanism by which the brain's hundred billion neurons and hundred trillion synapses manage to produce such a range of cortical ...
A Cavagna, A Levina, A Mazzoni, AG Garrity, BD Malamud, C Anteneodo, C Bedard, CF Beckmann, CJ Honey, CJ Stam, CV Stewart, CW Eurich, D Cordes, D Fraiman, D Plenz, D Zhang, Dante R. Chialvo, DL Gilden, DR Chialvo, DR Chialvo, E Balleza, E Bienenstock, E Bullmore, EA Maylor, ED Gireesh, EM Rauch, G Buzsaki, G Nicolis, G Werner, H Laufs, HJ Jensen, I Osorio, J Touboul, J Xiong, JAS Kelso, JAS Kelso, JJ Hopfield, JL Vincent, JM Beggs, JM Beggs, JN Teramae, JR Manning, JS Damoiseaux, K Christensen, K Linkenkaer-Hansen, KJ Miller, L de Arcangelis, LM Ward, M Aldana, M Beekman, M Buchanan, M Fukunaga, M Nykter, M Takayasu, MD Fox, MG Kitzbichler, MN Baliki, MO Magnasco, MP van den Heuvel, NK Logothetis, O Kinouchi, O Peters, O Peters, O Peters, O Sporns, P Anderson, P Bak, P Bak, P Bak, P Bak, R Beckers, R Eckhorn, R Salvador, S Zapperi, SJ Broyd, SM Smith, T Lux, T Nakamura, T Petermann, TH Bullock, V Pasquale, VM Eguiluz, Y He, Y Kuramoto   +83 more
core   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Multiple groups of neurons in the superior colliculus convert value signals into saccadic vigor

iScience
Summary: Eye movements toward high-valued objects are executed with greater vigor. To test how neurons in the superior colliculus (SC), a subcortical structure that controls these movements, are modulated by value, we recorded four SC neuron subtypes ...
Atul Gopal, Okihide Hikosaka
doaj   +1 more source

A Logic Model of Neuronal-Glial Interaction Suggests Altered Homeostatic Regulation in the Perpetuation of Neuroinflammation

Frontiers in Cellular Neuroscience, 2018
Aberrant inflammatory signaling between neuronal and glial cells can develop into a persistent sickness behavior-related disorders, negatively impacting learning, memory, and neurogenesis.
Travis J. A. Craddock, Travis J. A. Craddock, Travis J. A. Craddock, Travis J. A. Craddock, Lindsay T. Michalovicz, Kimberly A. Kelly, Mark A. Rice, Diane B. Miller, Nancy G. Klimas, Nancy G. Klimas, Nancy G. Klimas, Mariana Morris, Mariana Morris, James P. O'Callaghan, Gordon Broderick, Gordon Broderick, Gordon Broderick   +16 more
doaj   +1 more source

An embodied and grounded perspective on concepts [PDF]

, 2015
By the mainstream view in psychology and neuroscience, concepts are informational units, rather stable, and are represented in propositional format.
Borghi, ANNA MARIA
core  

BluePyOpt: Leveraging open source software and cloud infrastructure to optimise model parameters in neuroscience

, 2016
At many scales in neuroscience, appropriate mathematical models take the form of complex dynamical systems. Parametrising such models to conform to the multitude of available experimental constraints is a global nonlinear optimisation problem with a ...
Chindemi, Giuseppe, Courcol, Jean-Denis, Gevaert, Michael, Markram, Henry, Muller, Eilif, Rössert, Christian, Schürmann, Felix, Segev, Idan, Van Geit, Werner   +8 more
core   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Orthogonal spectral and temporal envelope representation during the onset phase in auditory cortex

iScience
Summary: Speech perception relies on two fundamental acoustic components: spectral and temporal. While spectral information is known to be represented in the auditory cortex through tonotopy, how temporal features are organized has remained unclear. Here,
Kuniyuki Takahashi, Tianrui Guo, Tatsuya Yamagishi, Shinsuke Ohshima, Hiroaki Tsukano, Arata Horii   +5 more
doaj   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source