Results 81 to 90 of about 779,188 (287)
, 2016 Bursting is a phenomenon found in a variety of physical and biological systems. For example, in neuroscience, bursting is believed to play a key role in the way information is transferred in the nervous system.
Bernard, Christophe +3 more
core +3 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Vision: A Systems Neuroscience Perspective
The Journal of Neurobehavioral Sciences, 2014 The visual system is the most studied part of the cortex, providing a basis for understanding not only visual processing per se but also the fundamentals operations of the brain in general. Significant progress has been made in understanding neural structures sensitive to different visual attributes such as form, surface brightness, color and motion ...
openaire +3 more sources
System neuroscience: Past, present, and future [PDF]
CNS Neuroscience & Therapeutics, 2018 SummaryIn this review, we discuss first the anatomical and lesion studies that allowed the localization of fundamental functions in the cerebral cortex of primates including humans. Subsequently, we argue that the years from the end of the Second World War until the end of the last century represented the “golden age” of system neuroscience.
Rizzolatti G +3 more
openaire +3 more sources
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
iScienceSummary: Stimulus-specific adaptation is a key feature of sensory systems, where the repeated presentation of a stimulus results in diminishing neuronal responses specifically to that stimulus, but not to a different stimulus.
Philip T.R. Bender +6 more
doaj +1 more source
Semi-automatic Database Design for Neuroscience Experiment Management Systems [PDF]
, 2004 Neuroinformatics provides tools for neuroscience researchers to study brain function. In order to handle experiment paradigms that change frequently, we are developing a semiautomatic database design tool that will enable an experiment management system (
Brinkley, James F +2 more
core +1 more source
Form and function in systems neuroscience [PDF]
Current Biology, 2006 'Form follows function' is an architectural philosophy attributed to the great American architect Louis Sullivan, and later taken up by the Bauhaus movement. It stresses that the form of a building should reflect its function. Neuroscientists have used the converse of this dictum to learn the functions of neural circuits, believing that if we study ...
Kristan, William B., Katz, Paul
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
Nonspecific ensemble reactivation in mouse dentate gyrus disrupts spatial working memory
iScienceSummary: Spatial working memory enables behavioral flexibility and depends upon the hippocampus. The hippocampal dentate gyrus (DG) is hypothesized to act as a pattern separator to disambiguate similar memories.
Lucius K. Wilmerding +4 more
doaj +1 more source