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Nine insights from internet engineering that help us understand brain network communication
Frontiers in Computer Science, 2023 Philosophers have long recognized the value of metaphor as a tool that opens new avenues of investigation. By seeing brains as having the goal of representation, the computer metaphor in its various guises has helped systems neuroscience approach a wide ...
Daniel J. Graham
doaj +1 more source
Building sustainable neuroscience capacity in Africa : the role of non-profit organisations [PDF]
, 2015 While advances in neuroscience are helping to improve many aspects of human life, inequalities exist in this field between Africa and more scientifically-advanced continents.
Cobham, Ansa E. +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
iScience, 2021 Summary: Alzheimer's disease (AD) is a worldwide burden. Diagnosis is complicated by the fact that AD is asymptomatic at an early stage. Studies using AD-modeled animals offer important and useful insights. Here, we classified mice with a high risk of AD
Stephanie Sutoko +6 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Biology, 2022 Studying how spatially discrete neuroanatomical regions across the brain interact is critical to advancing our understanding of the brain. Traditional neuroimaging techniques have led to many important discoveries about the nature of these interactions ...
Dylan J. Terstege, Jonathan R. Epp
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, 2018 Developing whole-brain emulation (WBE) technology would provide immense benefits across neuroscience, biomedicine, artificial intelligence, and robotics.
Collins, Logan Thrasher
core +1 more source
Beware of the Small-World neuroscientist! [PDF]
, 2016 The SW has undeniably been one of the most popular network descriptors in the neuroscience literature. Two main reasons for its lasting popularity are its apparent ease of computation and the intuitions it is thought to provide on how networked systems ...
Buldú, Javier M. +3 more
core +4 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Why do mice squeak? Toward a better understanding of defensive vocalization
iScience, 2022 Summary: Although mice mostly communicate in the ultrasonic range, they also emit audible calls. We demonstrate that mice selectively bred for high anxiety-related behavior (HAB) have a high disposition for emitting sonic calls when caught by the tail ...
Julia Ruat +7 more
doaj +1 more source