Results 121 to 130 of about 2,242,763 (316)
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
, 2003 The overall goal of the project was to develop methodology for the fabrication of a fluted spiral module, produce a prototype module and test its performance. This goal was to be achieved in several stages as follows: Formation of Fluted Membrane Leaf--A
Systems, Scinep
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Stabilizability of bimodal piecewise linear systems with continuous vector field
, 2006 Çamlıbel, Mehmet Kanat (Dogus Author)This paper studies the open-loop stabilization problem for bimodal systems with continuous vector field. It is based on the earlier work of the authors on the controllability problem for the same class of systems.
Schumacher, Hans +2 more
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DronesUncrewed aircraft systems are expected to revitalize traffic activities at under-utilized airports. These airports are often located in uncontrolled airspace and do not have an operating control tower to provide separation services for approaching ...
Tim Felix Sievers +6 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Web information systems: A study of maintenance, change and flexibility
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Information Systems (IS’s) have provided organisations with huge efficiency gains and benefits over the years; however an outstanding problem that is yet to
Peters, Jason Christian
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
User participation and user satisfaction in information systems development
, 2001 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 26/06/2001.Information Systems (IS) are being developed and used in organizations to achieve their business goals and to enhance organizational ...
Bokhari, Rahat Hussain, Bokhari, R.H.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2005 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Our work will be mainly concerned with improving the crucial first stage (the requirements stage) of any system development methodology in order to improve ...
Al-Karaghouli, Wafi Yousif Ramadaan
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