Results 61 to 70 of about 1,643,891 (268)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Silicon nano-kirigami with controlled plastic, elastic and hysteretic deformations

Nature Communications
Nano-kirigami, inspired by the art of paper cutting and folding, offers a promising approach to three-dimensional (3D) nanomanufacturing by simply transforming two-dimensional (2D) precursors into complex 3D architectures. Here we report a profound study
Qinghua Liang, Zhiguang Liu, Yu Han, Shang Chen, Haozhe Sun, Yingying Chen, Yongyue Zhang, Meihua Niu, Chongrui Li, Yang Wang, Ke Jin, Yongtian Wang, Yugui Yao, Juan Liu, Jiafang Li   +14 more
doaj   +1 more source

The Entanglement Structure of Quantum Field Systems [PDF]

International Studies in the Philosophy of Science, 2013
This article discusses the peculiar features of quantum entanglement and quantum non-locality within the algebraic approach to relativistic quantum field theory (RQFT). The debate on the ontology of RQFT is considered in the light of these well-known but little discussed features.
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Imaging of coherent fields through lenslike systems [PDF]

Optics Letters, 1994
I derive the imaging condition for the complex amplitude of a monochromatic field by a sequence of lens-like elements.
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Prevalence and factors associated with pre-diabetes and diabetes mellitus in Kenya: results from a national survey

BMC Public Health, 2018
Background Diabetes Mellitus is one of the four major non-communicable diseases causing about 4 million deaths in 2017. By 2040, low income countries are projected to experience 92% increase in mortality due to diabetes.
Shukri F Mohamed, Martin Mwangi, Martin K Mutua, Joseph Kibachio, Abubakar Hussein, Zachary Ndegwa, Scholastica Owondo, Gershim Asiki, Catherine Kyobutungi   +8 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Light dark matter search with nitrogen-vacancy centers in diamonds

Journal of High Energy Physics
We propose an approach to directly search for light dark matter, such as the axion or the dark photon, by using magnetometry with nitrogen-vacancy centers in diamonds. If the dark matter couples to the electron spin, it affects the evolution of the Bloch
So Chigusa, Masashi Hazumi, Ernst David Herbschleb, Norikazu Mizuochi, Kazunori Nakayama   +4 more
doaj   +1 more source

Mean Field Analysis of Low–Dimensional Systems [PDF]

Communications in Mathematical Physics, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources