Results 101 to 110 of about 37,129,814 (295)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 19 (1984)

, 1983
TWENTY EIGHTH ANNUAL MEETING / April 7, 1984 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association ...
Arizona-Nevada Academy of Science
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 21 (1986)

, 1986
THIRTIENTH ANNUAL MEETING / April 19, 1986 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association / Glendale ...
Arizona-Nevada Academy of Science
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Designing computer-supported complex systems curricula for the next generation science standards in high school science classrooms [PDF]

, 2016
We present a curriculum and instruction framework for computer-supported teaching and learning about complex systems in high school science classrooms. This work responds to a need in K-12 science education research and practice for the articulation of ...
Evans, Chad, Murat Oztok, Yoon, Susan, Anderson, Emma, Emma Anderson, Susan Yoon, Daniel Wendel, Hal Scheintaub, Josh Sheldon, Chad Evans, Goh, Sao-Ee, Wendel, Daniel, Jessica Koehler-Yom, Oztok, Murat, Schoenfeld, Ilana, Scheintaub, Hal, Sheldon, Joshua, Susan A. Yoon, Klopfer, Eric, Sheldon, Josh, Koehler-Yom, Jessica, Ilana Schoenfeld, Sao-Ee Goh, Eric Klopfer, Yoon, Susan A., Wendel, Daniel J   +25 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 23 (1988)

, 1988
THIRTY-SECOND ANNUAL MEETING / April 16, 1988 / Participating Societies - Arizona Junior Academy of Science, American Water Resources Association, Arizona Hydrological Society / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona ...
Arizona-Nevada Academy of Science
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