Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Air Force Systems Command Technical Documentary Report 61-453
Report discussing a study initiated to investigate and apply techniques of microminiaturization to circuits designed for high reliability performance with two goals: (1) to develop ultra-reliability design techniques in communication equipment, and (2 ...
Anderson, George +1 more
core
Systems science methods reveal and address links between discrimination and health disparities in US food systems. [PDF]
Moore TR +11 more
europepmc +1 more source
Incorporating Microbial Species Interaction in Management of Freshwater Toxic Cyanobacteria: A Systems Science Challenge. [PDF]
Banerji A, Benesh K.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Effect of early clinical exposure based health systems science course in the Korean medical education: a prospective observational study. [PDF]
Lee HY, Im S, Shin SW, Kim JA, Song JM.
europepmc +1 more source
Collaborative learning health systems: Science and practice. [PDF]
Hartley DM, Seid M.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Health systems science education for undergraduate medical students: a 3-year longitudinal curriculum preparing students to drive real-world health system improvement. [PDF]
Popatia R +5 more
europepmc +1 more source
Increasing use of systems science in cardiovascular disease prevention to understand how to address geographic health disparities in communities with a disproportionate burden of risk. [PDF]
Bauer KL +4 more
europepmc +1 more source

