Results 191 to 200 of about 2,984,717 (307)

Bridging Theory and Practice: a qualitative study on electronic charting and health systems science in Korean medicine education in alignment with KAS2022. [PDF]

J Pharmacopuncture
Lee WT, Kim BM, Choi HY, Kim SK, Park SE.   +4 more
europepmc   +1 more source

Implementation of simulation-based health systems science modules for resident physicians. [PDF]

BMC Med Educ, 2022
Li L, Ray JM, Bathgate M, Kulp W, Cron J, Huot SJ, Wong AH.   +6 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Systems science methods reveal and address links between discrimination and health disparities in US food systems. [PDF]

Nat Food
Moore TR, Krobath DM, Chang Chusan YA, Sanga U, Webb P, Pachucki M, Cuevas A, Roland HB, Grant B, Economos CD, Nicholson V, Kumanyika S.   +11 more
europepmc   +1 more source

Building Culturally Centered System Dynamics Logic Models for the Brown Buttabean Motivation Organization: Protocol for a Systems Science Approach. [PDF]

JMIR Res Protoc, 2023
Savila F, Harding T, Swinburn B, Bagg W, Letele D, Laban F, Goodyear-Smith F.   +6 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Effect of early clinical exposure based health systems science course in the Korean medical education: a prospective observational study. [PDF]

BMC Med Educ
Lee HY, Im S, Shin SW, Kim JA, Song JM.
europepmc   +1 more source

Incorporating Microbial Species Interaction in Management of Freshwater Toxic Cyanobacteria: A Systems Science Challenge. [PDF]

Aquat Ecol, 2022
Banerji A, Benesh K.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Transdisciplinary perspectives for health systems science. [PDF]

Npj Health Syst
Bian J, Liu N, Overgaard SM, Padman R, Steel PAD, Tiase V, Whitcomb CA, Zhang J, Zhang Y.   +8 more
europepmc   +1 more source