Results 201 to 210 of about 2,984,717 (307)

Collaborative learning health systems: Science and practice. [PDF]

Learn Health Syst, 2021
Hartley DM, Seid M.
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Health systems science education for undergraduate medical students: a 3-year longitudinal curriculum preparing students to drive real-world health system improvement. [PDF]

BMC Med Educ
Popatia R, D'Silva J, Stanley A, Khan N, Ho SB, Alsheikh-Ali A.   +5 more
europepmc   +1 more source

Increasing use of systems science in cardiovascular disease prevention to understand how to address geographic health disparities in communities with a disproportionate burden of risk. [PDF]

Front Cardiovasc Med, 2023
Bauer KL, Haapanen KA, Demeke N, Fort MP, Henderson KH.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Governance of Indigenous data in open earth systems science. [PDF]

Nat Commun
Jennings L, Jones K, Taitingfong R, Martinez A, David-Chavez D, Alegado Rʻ, Tofighi-Niaki A, Maldonado J, Thomas B, Dye D, Weber J, Spellman KV, Ketchum S, Duerr R, Johnson N, Balch J, Carroll SR.   +16 more
europepmc   +1 more source

Highlighting a curricular need: Uncertainty, COVID-19, and health systems science. [PDF]

Health Sci Rep, 2021
Papanagnou D, Jaffe R, Ziring D.
europepmc   +1 more source

The System of Sciences

This is the accreditation of the system of new appliwerd chemistry in 2025 for the new applications in applied chemistry for the sciences as a one pakage of the sciences in the studies this accreditation by Abdul Kareem Oath for the Sciences of everythuing about everything as a one stage nvalue for accredited zero system dfor the highest level of the ...
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Addressing the Increasing Rate of Caesarean Sections in an Australian Healthcare System: A Systems Science Approach to Identify Stakeholder Perspectives. [PDF]

Nurs Health Sci
O'Halloran S, Perlen S, Chapman A, Luba S, Dawson SL, Cusworth R, Alston L, Vasilevski V, Sweet L, Vuillermin P, Hutchinson AM, Pregnancy Research and Translation Ecosystem Investigator group.   +11 more
europepmc   +1 more source