Results 101 to 110 of about 2,005,886 (312)
Numerical study of variable lung ventilation strategies
, 2015 Mechanical ventilation is used for patients with a variety of lung diseases. Traditionally, ventilators have been designed to monotonously deliver equal sized breaths.
Bagler, Ganesh +3 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Individual emergence in contextual analysis [PDF]
, 2007 Located within the tradition of Hermeneutic Dialectics (HD) this paper offers an approach which can further an analysis of a fit between information and organizational systems.
Bednar, Peter
core
Nonexistence of Chaotic Solutions of Nonlinear Differential Equations
, 2011 We discuss some important issues arising from computational efforts in dynamical systems and fluid dynamics. Various individuals have misunderstood these issues since the onset of these problem areas; indeed, they have been routinely misinterpreted, and ...
Yao, Lun-Shin
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Systems Thinking Education—Seeing the Forest through the Trees
Systems, 2018 Systems thinking is an indispensable tool in comprehending and analyzing real-world phenomena. Observed processes are naturally composed of many interconnected components which ought to be studied jointly rather than individually.
Sigal Koral Kordova +2 more
doaj +1 more source
Systems thinking and Equity-focused evaluations
, 2012 Questions about access to resources - who gets what? - ought not to be seen in isolation from related questions of power - who owns what? They also ought not to be seen in isolation from questions of knowledge and expertise - who does what?
Reynolds, Martin, Williams, Bob
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
SystemsCyberattacks increasingly generate systemic economic and geopolitical effects in an era of dense global interdependence. While prior research emphasises geopolitical rivalry, institutional capacity, and technological sophistication as determinants of ...
Zlatan Morić +2 more
doaj +1 more source
On the design of systems-oriented university curricula
, 2009 This paper proposes a tool called the Systems Education Matrix (SEM) for use in informing the work of developers of systems-oriented curricula at colleges and universities around the world.
Bosch, Ockie +4 more
core