Results 231 to 240 of about 108,508 (278)

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari, Ruud H. J. Verstegen, Cintia Cruz, Erin Chung, Aleena Azim, Shinya Ito, Tamorah R. Lewis   +6 more
wiley   +1 more source

Rethinking "Control" in Micro- and Nanoplastic Toxicology: Toward Exposure-Defined Reference States. [PDF]

Environ Sci Technol
Shruti VC, Kutralam-Muniasamy G.
europepmc   +1 more source

Quality assessment of the forensic surveillance system: A data-quality monitoring system for substance-abuse detection in unnatural deaths in Thailand. [PDF]

Forensic Sci Int Synerg
Traisathit P, Worasuwannarak W, Aramrattana A, Angkurawaranon C, Jiraporncharoen W, Buawangpong N, Intui K, Rankantha A, Thanuta Y, Srikummoon P.   +9 more
europepmc   +1 more source

Evidence-based AI: from trailblazer to trustblazer? [PDF]

Front Artif Intell
Luechtefeld T, Hartung T.
europepmc   +1 more source

Regulatory integration of new approach methodologies for human-relevant developmental and reproductive toxicity (DART) assessment: A systematic cross-sector review. [PDF]

Toxicol Rep
Kumbhar S, Borude S, Deshmukh R.
europepmc   +1 more source

Systems toxicology: applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology

Expert Review of Proteomics, 2005
Toxicogenomics can facilitate the identification and characterization of toxicity, as illustrated in this review. Toxicogenomics, the application of the functional genomics technologies (transcriptomics, proteomics and metabolomics) in toxicology enables the study of adverse effects of xenobiotic substances in relation to structure and activity of the ...
Anne S Kienhuis, Ben Van Ommen, Rob H Stierum   +2 more
exaly   +6 more sources

In Vitro Toxicology Systems [PDF]

, 2014
In vitro toxicology systems , In vitro toxicology systems , کتابخانه مرکزی دانشگاه علوم پزشکی ...
Wilmes, A., Limonciel, A.V.S., Leonard, Martin O, Jennings, P.   +3 more
core   +6 more sources

Computational Systems Toxicology

, 2015
Toxicogenomics is an emerging field defined by the adaptation and application of functional genomics techniques to toxicology. Recent advances in generating and analyzing multi-omics data have facilitated the development of toxicogenomics to provide novel answers to many toxicology-related questions.
Constantinescu, Simona, Sturla, Shana J, Marra, Giancarlo, Wollscheid, Bernd, Beerenwinkel, Niko   +4 more
core   +3 more sources

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Toward an integrative systems toxicology

Pharmacogenomics, 2004
10.1517/14622416.5.8.1163 © Assessing toxicity is among the most ancient and important of human endeavors. Long before the taming of fire or the advent of tool use, humankind was confronted with a most basic problem of existence: what to ingest. Today, toxicology impacts every facet of our lives – from the food, supplements and therapeutics that we ...
Patrick Hurban
exaly   +3 more sources