FEBS Letters, EarlyView.We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring +6 more
wiley +1 more source
Multi-Mycotoxin Analysis in Durum Wheat Pasta by Liquid Chromatography Coupled to Quadrupole Orbitrap Mass Spectrometry [PDF]
, 2017 A simple and rapid multi-mycotoxin method for the determination of 17 mycotoxins simultaneously is described in the present survey on durum and soft wheat pasta samples. Mycotoxins included in the study were those mainly reported in cereal
Chianese, Donato +6 more
core +2 more sources
Radioimmunoassay of T-2 Toxin in Biological Fluids
Journal of AOAC INTERNATIONAL, 1981 Abstract A simple radioimmunoassay (RIA) for detection of T-2 toxin in biological fluids was developed. The method, which involves a Sep-Pak C18 reverse phase column cleanup step before RIA, can detect 0.5 ppb T-2 toxin in serum and 2.5 ppb T-2 toxin in urine and milk. Recoveries for toxin added to serum and urine or milk samples were 87-
Sungsoo C. Lee, Fun S. Chu
openaire +3 more sources
Efficacy of turmeric (Curcuma longa) to ameliorate the adverse effects of T-2 toxin in broiler chicks [PDF]
, 2008 only availableA 3-wk feeding study was conducted to evaluate the efficacy of turmeric (Curcuma longa) powder (TMP), containing a known level of curcumin to ameliorate the adverse effects of T-2 toxin in broiler chicks.
Ledoux, David R. (David Randolph), 1952- +1 more
core
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Effect of long term feeding of T-2 and HT-2 toxin contaminated diet on the glutathione redox status and lipid peroxidation processes in common carp (Cyprinus carpio L.) [PDF]
, 2009 Effect of sublethal T-2 (2.45 mg kg-1 feed) and HT-2 (0.52 mg kg-1 feed) toxin treatment for 4 weeks was investigated in common carp. Two groups, a control and a T-2+HT-2 toxin treated were formed.
Balogh, Krisztián
core
Mast cell activation by pedicellarial toxin of sea urchin, Toxopneustes pileolus [PDF]
, 1927 Pedicellarial toxin, partially purified from the sea urchin Toxopneustes pileolus, dose-dependently and time-dependently caused histamine release from rat peritoneal mast cells.
Masao Takei +33 more
core +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Effect of T-2 toxin and antioxidants on angel wing incidence and severity in White Roman geese
Journal of Applied Animal Research, 2018 This study investigates the effects of T-2 toxin and antioxidants on the incidence and severity of angel wing in White Roman geese. Twelve pens were used in this study, and half of them received dietary supplementation of T-2 toxin (10 ppm) and ...
Min-Jung Lin +5 more
doaj +1 more source
Shiga Toxin Detection Methods : A Short Review [PDF]
arXiv, 2013 The Shiga toxins comprise a family of related protein toxins secreted by certain types of bacteria. Shigella dysenteriae, some strain of Escherichia coli and other bacterias can express toxins which caused serious complication during the infection. Shiga toxin and the closely related Shiga-like toxins represent a group of very similar cytotoxins that ...
arxiv