Results 121 to 130 of about 399,149 (348)

Simultaneous Effect of Temperature and Irradiance on Growth and Okadaic Acid Production from the Marine Dinoflagellate Prorocentrum belizeanum [PDF]

open access: yes, 2014
Benthic marine dioflagellate microalgae belonging to the genus Prorocentrum are a major source of okadaic acid (OA), OA analogues and polyketides. However, dinoflagellates produce these valuable toxins and bioactives in tiny quantities, and they grow ...
Belarbi, El Hassan   +6 more
core   +3 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

An application of the Gyárfás path argument [PDF]

open access: yesarXiv, 2019
We adapt the Gy\'{a}rf\'{a}s path argument to prove that $t-2$ cops can capture a robber, in at most $t-1$ moves, in the game of cops and robbers played in a graph that does not contain the $t$-vertex path as an induced subgraph.
arxiv  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Effect of T-2 Toxin in Combination with Vitamin E, Selenium and Mycotoxin Binder on Lipid Peroxide Status and on the Glutathione Redox System in Broiler Chicken

open access: yesThe Journal of Poultry Science, 2006
The effect of T-2 toxin (2.35mg/kg of feed) on lipid peroxidation and on the antioxidant defence system was studied in blood plasma, red blood cells (RBC), liver and spleen of broiler chickens. The influences of antioxidant vitamin E (10.5mg/animal/day)+
Mária Weber   +3 more
doaj   +1 more source

Trichothecenes and zearalenone production by Fusarium equiseti and Fusarium semitectum species isolated from Argentinean soybean [PDF]

open access: yes, 2012
Fusarium equiseti and F. semitectum represent the most abundant species in the Fusarium complex isolated from flowers, soybean pods and seeds in Argentina.
Alaniz Zanon, Maria Silvina   +5 more
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

The receptor-toxin-antibody interaction: Mathematical model and numerical simulation [PDF]

open access: yesarXiv, 2012
A reaction-diffusion model of receptor-toxin-antibody (RTA) interaction is studied numerically. The protective properties of an antibody against a given toxin are evaluated for a spherical cell placed into a toxin-antibody solution. The selection of parameters for numerical simulation approximately corresponds to the practically relevant values ...
arxiv  

Kontaminacija gljivama i prirodna pojava T-2 toksina u hrani za živinu [PDF]

open access: yes, 2014
In this study, a total of 41 poultry (chicken and laying hens) feed samples collected from different farms in Serbia in the beginning of 2014 were investigated for total fungal count, presence of potential toxigenic fungi and natural occurrence of T-2 ...
Bijelić, Zorica   +6 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

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