Results 181 to 190 of about 921 (215)

Cross-reactivity of antibodies against T-2 with deepoxide T-2 toxin

Mycotoxin Research, 1988
Two types of antibodies raised against T-2 toxin, namely anti-T-2-HS-BSA and anti-3 -Ac -NEOS-HS -BSA, showed good cross-reactivity with deepoxy T-2 toxin. Our results indicate that the epoxide is not an important epitope for the production of antibody against T-2 toxin.
R D, Wei, S P, Swanson, F S, Chu
openaire   +2 more sources

A monoclonal antibody to T-2 toxin

Letters in Applied Microbiology, 1987
A specific, high affinity monoclonal antibody to T-2 toxin of Fusarium has been produced. The monoclonal antibody was conjugated to horse-radish peroxidase and employed to develop a direct competitive enzyme-linked immunosorbent assay (ELISA) for the toxin. The sensitivity of the ELISA was 10 ng/ml with a working range up to 500 ng/ml.
I. A. GOODBRAND, W. H. STIMSON, I. E. SMITH   +2 more
openaire   +1 more source

A yeast bioassay for T-2 toxin

Journal of Microbiological Methods, 1984
Abstract A disk diffusion type bioassay was developed for T-2 toxin using the yeast Kluyveromyces fragilis . The lower limit of detection for this in 0.2 μg of T-2 toxin. The growth of this yeast was sensitive to other trichothecenes such as verrucarin A (0.01 μg).
K.T. Schappert, G.G. Khachatourians
openaire   +1 more source

HPLC: A Tool for the Analysis of T-2 Toxin and HT-2 Toxin in Cereals

Journal of Analytical Toxicology, 1984
An analytical procedure for the determination of trichothecenes in various cereals is described. HPLC was performed with a reversed-phase (C18) column eluted with methanol:water (60:40, v/v). Compounds were detected with a refractive index detector. The elution patterns of free and contaminated samples were compared.
R, Schmidt, K, Dose
openaire   +2 more sources

Effects of feeding T-2 toxin to rats and monkeys

Food and Cosmetics Toxicology, 1980
Abstract Feeding a diet containing mouldy sorghum that supplied 25 ppm T-2 toxin per day to rats for 16 wk produced marked growth depression and loss of body fur. No other clinical signs or histopathological changes were observed. Semi-purified T-2 toxin was obtained from rice culture by a series of extraction procedures and was free of other ...
C, Rukmini, J S, Prasad, K, Rao
openaire   +2 more sources

A Proposed Immunoassay for T-2 Toxin

1990
Previously (Uneo, 1983; Dashek et al., 1985; Lacey, 1985) reviewed the evidence regarding the alleged utilization of certain trichothecenes as biological warfare agents and the biological effects and chemistry of the trichothecenes as well as the fungi which produce them.
Charles E. O’Rear, Nicholas T. Lappas, William V. Dashek, Gerald C. Llewellyn   +3 more
openaire   +1 more source

Toxicological Features of T-2 Toxin and Related Trichothecenes

Toxicological Sciences, 1984
Toxicological characteristics of T-2 toxin and related trichothecenes, mycotoxins produced by Fusarium, Trichoderma, Verrucaria, and others, were investigated in regard to LD50 values, dermal toxicity, hematological changes, and tumorigenicity. The LD50 values (mg/kg) of T-2 toxin in adult male mice were po 10.5, ip 5.2, sc 2.1, and iv 4.2, and those ...
openaire   +2 more sources

Synthesis of radiolabeled T-2 toxin

Journal of Agricultural and Food Chemistry, 1977
E M, Wallace, S V, Pathre, C J, Mirocha, T S, Robison, S W, Fenton   +4 more
openaire   +2 more sources

T-2 toxin degradation by micromycetes.

Journal of hygiene, epidemiology, microbiology, and immunology, 1991
The biodegradation of T-2 toxin was studied by strains of micromycetes which were isolated from the environment. The 26 tested strains were divided into three groups. Group contains strains which degraded T-2 toxin very fast. This toxin could not be chromatographically determined in the medium even after 48 hours of incubation and the antifungal ...
Z, Jesenská, I, Sajbidorová
openaire   +1 more source

Toxin-Antitoxin Systems as Phage Defense Elements

Annual Review of Microbiology, 2022
Michael T Laub, Michele Leroux
exaly