T-2 mycotoxin Induces male germ cell apoptosis by ROS-mediated JNK/p38 MAPK pathway
Ecotoxicology and Environmental Safety, 2023 T-2 mycotoxin, a type A trichothecene toxin that, specifically, causes male and female reproductive toxicity. We evaluated T-2 toxin toxicity in testes from neonatal testes after in vitro tissue cultured.
Won-Young Lee, Hyun-Jung Park
doaj
p38 mediates T-2 toxin-induced Leydig cell testosterone synthesis disorder
Ecotoxicology and Environmental Safety, 2023 T-2 toxin is an unavoidable food and feed contaminant that seriously threatens human and animal health. Exposure to T-2 toxin can cause testosterone synthesis disorder in male animals, but the molecular mechanism is still not completely clear.
Xu Yang +9 more
doaj
Survey for Fusaria That Elaborate T-2 Toxin [PDF]
Applied Microbiology, 1972 Of the 136 strains of Fusarium examined, T-2 toxin was confirmed by thinlayer chromatography in 13 of the 21 extracts that inhibited either Rhodotorula rubra or Pencillium digitatum .
Clifford W Hesseltine +2 more
openaire +3 more sources
T-2 mycotoxin slows down the development of mouse blastocysts, decreases their blastomere number and increases chromatin damage [PDF]
, 2016 The mycotoxin T-2 has many harmful effects on mammalian cells and reproductive functions. In the present study, the in vitro effect of T-2 toxin on mouse blastocysts was examined. Embryos were cultured in media supplemented with 0.5, 0.75 and 1 ng/ml T-2.
Cseh, Sándor +2 more
core +1 more source
Effect of a Mycotoxin Binder (MMDA) on the Growth Performance, Blood and Carcass Characteristics of Broilers Fed Ochratoxin A and T-2 Mycotoxin Contaminated Diets [PDF]
, 2021 The contamination of feed with mycotoxins is a global concern, resulting in adverse effects on productivity and animal health and, therefore, a great economic loss.
Farkas, Hunor +6 more
core +2 more sources
Using Multiscale Molecular Dynamics Simulations to Obtain Insights into Pore Forming Toxin Mechanisms [PDF]
Methods in Enzymology (Chapter Sixteen), 2021, 2020 Pore forming toxins (PFTs) are virulent proteins released by several species, including many strains of bacteria, to attack and kill host cells. In this article, we focus on the utility of molecular dynamics (MD) simulations and the molecular insights gleaned from these techniques on the pore forming pathways of PFTs.
arxiv +1 more source
Ecotoxicology and Environmental Safety, 2022 T-2 toxin belongs to the trichothecenes group A compound, mainly produced by Fusarium fungi. It has been shown that T-2 toxin could cross the placental barrier and breast milk, thus endangering the health of offspring.
Ruifen Kang +4 more
doaj
The Incidence of T-2 and HT-2 Toxins in Cereals and Methods of their Reduction Practice by the Food Industry [PDF]
, 2017 T-2 toxin and its major metabolite HT-2 toxin are type A trichothecene mycotoxins produced by the Fusarium moulds, present mainly in cereals and cereal-based products.
Babić, Jurislav +3 more
core +1 more source
The role of mitochondria in T-2 toxin-induced human chondrocytes apoptosis. [PDF]
PLoS ONE, 2014 T-2 toxin, a mycotoxin produced by Fusarium species, has been shown to cause diverse toxic effects in animals and is also a possible pathogenic factor of Kashin-Beck disease (KBD). The role of mitochondria in KBD is recognized in our recent research. The
Jiangtao Liu +7 more
doaj +1 more source
Probing the interactions of ochratoxin B, ochratoxin C, patulin, deoxynivalenol, and T-2 toxin with human serum albumin [PDF]
, 2020 Ochratoxins, patulin, deoxynivalenol, and T-2 toxin are mycotoxins, and common contaminants in food and drinks. Human serum albumin (HSA) forms complexes with certain mycotoxins.
Csepregi, Rita +8 more
core +1 more source