Results 41 to 50 of about 2,650,641 (236)

T-2 toxin induces articular cartilage damage by increasing the expression of MMP-13 via the TGF-β receptor pathway

open access: yesHuman and Experimental Toxicology, 2022
T-2 toxin pre-disposes individuals to osteoarthritis, Kashin–Beck disease (KBD). The major pathological change associated with KBD is the degradation of the articular cartilage matrix.
Ying Zhang   +5 more
semanticscholar   +1 more source

Mitochondrial Damage Induced by T-2 Mycotoxin on Human Skin—Fibroblast Hs68 Cell Line

open access: yesMolecules, 2023
T-2 toxin is produced by different Fusarium species and belongs to the group of type A trichothecene mycotoxins. T-2 toxin contaminates various grains, such as wheat, barley, maize, or rice, thus posing a risk to human and animal health.
Edyta Janik-Karpinska   +5 more
doaj   +1 more source

In Vitro Detoxification of Aflatoxin B1, Deoxynivalenol, Fumonisins, T-2 Toxin and Zearalenone by Probiotic Bacteria from Genus Lactobacillus and Saccharomyces cerevisiae Yeast

open access: yesProbiotics and Antimicrobial Proteins, 2019
The aim of the following research was to determine the detoxification properties of probiotic Lactobacillus sp. bacteria (12 strains) and S. cerevisiae yeast (6 strains) towards mycotoxins, such as aflatoxin B1, deoxynivalenol, fumonisins, T-2 toxin and ...
A. Chlebicz, K. Śliżewska
semanticscholar   +1 more source

Efficacy of T-2 toxin detoxifying agent in broiler chickens [PDF]

open access: yesActa Veterinaria, 2012
This investigation was conducted in order to investigate the efficacy of the detoxifying agent Mycofix® Plus (MP) in the prevention and/or alleviation in vivo adverse effects of T-2 toxin in broilers.
Nešić V.   +6 more
doaj   +1 more source

Structure-function analysis of porcine cytochrome P450 3A29 in the hydroxylation of T-2 toxin as revealed by docking and mutagenesis studies. [PDF]

open access: yesPLoS ONE, 2014
T-2 toxin, one of the type A trichothecenes, presents a potential hazard to human and animal health. Our previous work demonstrated that porcine cytochrome P450 3A29 (CYP3A29) played an important role in the hydroxylation of T-2 toxin.
Guyue Cheng   +8 more
doaj   +1 more source

T-2 Toxin and Apoptosis

open access: yesJournal of Toxicologic Pathology, 2006
T-2 toxin is a cytotoxic fungal secondary metabolite produced by various species of Fusarium. This paper reviews the reported data about the development and/or mechanisms of T-2 toxin-induced apoptosis in the hematopoietic, lymphoid and gastrointestinal tissues, dorsal skin and fetal tissues of mice and rats.
Kunio Doi   +2 more
openaire   +2 more sources

miR449a/SIRT1/PGC-1α Is Necessary for Mitochondrial Biogenesis Induced by T-2 Toxin

open access: yesFrontiers in Pharmacology, 2018
T-2 toxin is one of the type A trichothecenes produced mainly by the Fusarium genus. Due to its broad distribution and highly toxic nature, it is of great concern as a threat to human health and animal breeding.
Shijie Ma   +8 more
doaj   +1 more source

Survey for Fusaria That Elaborate T-2 Toxin [PDF]

open access: yesApplied Microbiology, 1972
Of the 136 strains of Fusarium examined, T-2 toxin was confirmed by thinlayer chromatography in 13 of the 21 extracts that inhibited either Rhodotorula rubra or Pencillium digitatum .
H R, Burmeister   +2 more
openaire   +2 more sources

Effects of a Low Dose of T-2 Toxin on the Percentage of T and B Lymphocytes and Cytokine Secretion in the Porcine Ileal Wall

open access: yesToxins, 2021
Plant materials used in the production of pig feed are frequently contaminated with mycotoxins. T-2 toxin is a secondary metabolite of selected Fusarium species, and it can exert a harmful influence on living organisms. Most mycotoxins enter the body via
P. Wojtacha   +11 more
semanticscholar   +1 more source

Evaluation of mycofix to ameliorate the toxic effect of t-2 toxin on performance of broiler chickens [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2007
The possible protective effect of Mycofix against the toxic effect of T-2 toxin in growing broiler chickens was investigated in two age stages; the first and second ages, ranged from 1-21 and 22-42 days, respectively.
A. M. Shareef, Z. A. Jameel
doaj   +1 more source

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