Results 51 to 60 of about 30,760,761 (278)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
, 2013 Our Project provides a Meals on Wheels delivery Service and a Drop in Centre five days per week. Â We provide a three course meal which is made from only fresh local produce. Â All soup, breads, desserts etc. are homemade. Our dinner consists of homemade
Healthy Food For All
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Implementation of pharmacogenetics for treatment of patients with acute lymphoblastic leukemia
Research Results in PharmacologyIntroduction: Acute lymphoblastic leukemia (ALL) is the most frequent pediatric leukemia; it can be defined according to chromosomic and genomic data. Cytogenetic analyses and determination of chromosomal numbers (such as hypo- or hyperdiploidy) and/or ...
Violeta Graiqevci-Uka +4 more
doaj +1 more source
Cherry Orchard Community Garden
, 2014 Community garden project and allotments aims to increase community involvement, participation and activity in the locality. We have a number of family groups (parents and children) working together. It is a lot of fun and a great way to meet new people
Healthy Food For All
core +1 more source
Disorder‐Broadened Topological Hall Phase and Anomalous Hall Scaling in FeGe
Advanced Functional Materials, EarlyView.By systematically introducing defects into FeGe via ion‐beam modification, we demonstrate that disorder broadens the temperature regime over which the topological Hall effect ‐ a signature of skyrmions or other chiral textures — appears, while also increasing its magnitude.
Chaman Gupta +11 more
wiley +1 more source
Up to 16% Optical Carbon‐13 Hyperpolarization of Donor–Acceptor Molecules at 14.1 T
Angewandte Chemie, EarlyView.Up to 16% 13C nuclear polarization is achieved using a rationally designed photo‐CIDNP polarizing agent (PA) in magic‐angle‐spinning NMR experiments at 14.1 T. The PA was designed using a combination of theoretical photocycle calculations and magnetic field dependent experiments to identify important new design principles.
Marcel Levien +10 more
wiley +2 more sources
مجله كليه طب الكندي, 2014 Avascular necrosis have always presented great challenges to orthopedic surgeons and patients, remain in many ways today the unsolved dilemma. Varieties of non-vascularized bone grafting techniques preceded by core decompression have been proposed with
Baqer Kadhim Kraidi +1 more
doaj
Targeting Nonclassical Oncogenes for Therapy in T-ALL [PDF]
Cancer Cell, 2012 Constitutive phosphoinositide 3-kinase (PI3K)/Akt activation is common in T cell acute lymphoblastic leukemia (T-ALL). Although four distinct class I PI3K isoforms (α, β, γ, δ) could participate in T-ALL pathogenesis, none has been implicated in this process.
Subramaniam, Prem S. +13 more
openaire +2 more sources
Cloughmills Incredible Edibles Project
, 2013 Cloughmills Incredible Edibles Project aims to reconnect people with each other, their community and the natural world by developing a sustainable, fair and healthy food system in Cloughmills.
Healthy Food For All
core +1 more source