Results 41 to 50 of about 30,760,761 (278)

Groundwater level management in a reclamation system [PDF]

open access: yesBIO Web of Conferences
Soil fertility largely depends on the water regime of the territories. Yields on agricultural lands that are subject to flooding and waterlogging are low. On the other hand, lowering the groundwater level also negatively affects soil fertility.
Kolesnichenko Kristina   +3 more
doaj   +1 more source

mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells

open access: yesRedox Biology, 2022
mTOR activation is a hallmark of T-cell acute lymphoblastic leukemia (T-ALL) and is associated with resistance to glucocorticoid (GC)-based chemotherapy.
Micol Silic-Benussi   +15 more
doaj   +1 more source

The role of NOTCH1 signaling in T-ALL [PDF]

open access: yesHematology, 2009
AbstractThe identification of activating mutations in NOTCH1 in over 50% of T-cell acute lymphoblastic leukemias (T-ALL) has generated major interest in the elucidation of the mechanisms of transformation downstream of oncogenic NOTCH and in the targeting of the NOTCH signaling pathway in this disease. Small molecule γ-secretase inhibitors (GSIs) block
openaire   +2 more sources

The Attic Youth Cafe

open access: yes, 2013
The Attic Youth Cafe was established as a social inclusion initiative and response to the issues of early school leaving, lack of informal educational opportunities, early sexual activity, early use of alcohol and the lack of a recreational space for ...
Healthy Food For All
core   +1 more source

IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo

open access: yesOncoImmunology, 2017
NK cells have shown promise in therapy of hematological cancers, in particular against acute myeloid leukemia. In contrast, the more NK cell-resistant acute lymphoblastic leukemia (ALL) is difficult to treat with NK-cell-based therapies, and we ...
Margherita Boieri   +7 more
doaj   +1 more source

Hooked on Hes: A T-ALL of Addiction [PDF]

open access: yesImmunity, 2010
Hes1 is a direct Notch1 target; however, its precise function is unclear. In this issue of Immunity, Wendorff et al. (2010) report that Hes1 regulates the number of T cell progenitors and has important functions in both the induction and maintenance of T cell leukemia.
openaire   +2 more sources

Power for All: The Energy Access Imperative [PDF]

open access: yes, 2014
Power for All is a call to a different action for the policymakers, stakeholders, entrepreneurs and customers engaged in driving universal energy access for the billions of people without reliable power.Today, nearly one-third of the global population is
Donn Tice, Kristina Skierka
core  

Cup & Spoon Cafe

open access: yes, 2013
The Cup and Spoon Cafe at Ballyfermot Family Resource Centre offers all aspects of outside catering including; If you have a special occasion coming up and would like to have it catered for in your locality, then the Cup and Spoon is the perfect choice ...
Healthy Food For All
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Moville Community Garden

open access: yes, 2013
Promoting health both physical and mental in the community is part of the ethos of Moville FRC and the Community Garden is an important part of our programme. It encourages people to grow their own food and cook and eat healthily.
Healthy Food For All
core   +1 more source

Home - About - Disclaimer - Privacy