Results 121 to 130 of about 212,422 (259)

Genetic Variability and Conserved T-Cell Epitope Prediction of the HPV16 E1 Protein in Cervix Samples from Peru. [PDF]

Pathogens
Bonifacio-Velez de Villa E, Aguilar-Luis MA, Silva-Caso W, Becerra-Goicochea L, Tarazona-Castro Y, Aguilar-Luis D, Denegri-Hinostroza D, Cornejo-Tapia A, Aquino-Ortega R, Del Valle-Mendoza J.   +9 more
europepmc   +1 more source

Retracted: Machine Learning-Based Ensemble Model for Zika Virus T-Cell Epitope Prediction. [PDF]

J Healthc Eng, 2023
Healthcare Engineering JO.
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Foundation Protein Language Models for Influenza A Virus T-Cell Epitope Prediction: A Transformer-Based Viroinformatics Framework. [PDF]

Viruses
Bukhari SNH, Ogudo KA.
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Different clinical forms of Plasmodium vivax infection result in unique T cell epitope-specific immune responses. [PDF]

J Immunol
Costa CM, Almeida GG, Lindestam Arlehamn CS, Queiroz-Glauss CP, Gunderman VHG, Pereira MMM, Amaral LRD, Pereira DB, Tada MS, Martins-Filho OA, Gazzinelli RT, Antonelli LRDV.   +11 more
europepmc   +1 more source

Neo-intline: integrated pipeline enables neoantigen design through the in-silico presentation of T-cell epitope. [PDF]

Signal Transduct Target Ther, 2023
Li B, Jing P, Zheng G, Pi C, Zhang L, Yin Z, Xu L, Qiu J, Gu H, Qiu T, Fang J.   +10 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Decoding the human CD4⁺ T cell epitope repertoire for Lassa fever virus reveals T cell-based pan-mammarenavirus vaccine candidates. [PDF]

Cell Rep Med
Lee Y, Siddiqui L, Tarke A, Kim M, Michaelis T, Macias M, Phillips E, Mallal S, Trevizani R, Frazier A, Scheuermann RH, Zuniga A, Zmasek C, Spurgers K, Akintunde G, Stonier SW, Gagliardi TB, Warfield K, Li H, Hastie KM, Saphire EO, Tan GS, Grifoni A, Sette A.   +23 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source