Results 241 to 250 of about 2,656,822 (310)

Human CD3 complex is required for the generation of T-cell receptor-like chimeric antigen receptor targeting WT1 in natural killer cells. [PDF]

Cancer Immunol Immunother
Luanpitpong S, Poohadsuan J, Samart P, Kang X, Pratumkaew P, Janan M, Issaragrisil S.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

T cell receptor (TCR)-based therapy in advanced non-small cell lung cancer: a new hope? [PDF]

Transl Lung Cancer Res
Costantini A, Giroux Leprieur E.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection. [PDF]

Front Immunol
Zeng L, Liu L, Ren B, Feng B, Lai X, Lai X, Chen Z, Huang Y, Hong W.   +8 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Circulating T-cell receptor repertoire for cancer early detection. [PDF]

NPJ Precis Oncol
Li Y, Nahas M, Stephens D, Froburg K, Hintz E, Champagne D, Lochab A, Brown M, Braun J, Fortuño MA, Ocón MD, Pasquier A, Luque-Vázquez I, Moudgalya H, Kivlehan S, Gjeci I, Korle SL, Campo A, Rodriguez M, Seder CW, Lizotte PH, Bueno R, Borgia JA, Seijo LM, Montuenga LM, Yelensky R.   +25 more
europepmc   +1 more source

Conditional generation of real antigen-specific T cell receptor sequences. [PDF]

Nat Mach Intell
Karthikeyan D, Bennett SN, Reynolds AG, Vincent BG, Rubinsteyn A.   +4 more
europepmc   +1 more source

T cell receptor specificity landscape revealed through de novo peptide design. [PDF]

Proc Natl Acad Sci U S A
Visani GM, Pun MN, Minervina AA, Bradley P, Thomas PG, Nourmohammad A.   +5 more
europepmc   +1 more source

The geometry of pMHC-coated nanoparticles and T-cell receptor clusters governs the sensitivity-specificity trade-off in T-cell response: a modeling investigation. [PDF]

Immunol Cell Biol
Richez L, Khadra A.
europepmc   +1 more source