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Langerhans Cell Receptors

Dermatologic Clinics, 2007
Langerhans cells (LC) are a subtype of dendritic cells, which reside in the epidermis. LCs are antigen-presenting cells that originate in bone marrow and enter the epidermis through blood vessels. LCs exhibit a variety of antigen receptors that are able to respond to a wide range of antigens.
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T cell receptor signalling

Journal of Cell Science, 2001
Upon engagement of the TCR by antigen presented on major histocompatibility complex (MHC) molecules, the Src family kinase Lck is activated and proceeds to phosphorylate immunoreceptor tyrosine-based activation motifs (ITAMs) on the e, δ, γ and ζ subunits of the TCR.
Arthur Weiss, Joseph Lin
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T Cell Receptor Engineering

2012
T lymphocytes express on their surface a heterodimeric αβ receptor, called the T cell receptor (TCR), which recognizes foreign antigens. Unlike antibodies, the recognition requires both an antigenic peptide epitope and a protein encoded by the major histocompatibility complex (MHC).
David M. Kranz   +3 more
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High-throughput pairing of T cell receptor α and β sequences

Science Translational Medicine, 2015
T cell receptor α and β sequences can be accurately paired from hundreds of thousands of T cell clones in parallel. T cell receptor chains pair off High-throughput immunosequencing can take a snapshot of the repertoire of immune cells, providing a broad ...
Bryan N. Howie   +10 more
semanticscholar   +1 more source

Antibody and T-Cell Receptors

JAMA: The Journal of the American Medical Association, 1988
A VERTEBRATE is an attractive culture medium for viruses, bacteria, fungi, and metazoan parasites. It is therefore understandable that vertebrates have had to develop a body defense mechanism directed toward these pathogens for their emergence and survival. This defense mechanism is the See also pp 1834 and 1837. immune system.
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Cell receptors for paramyxoviruses

Archives of Virology, 1977
Treatment of chick embryo fibroblasts, calf kidney and BHK cells for 30 minutes with the enzyme neuraminidase from Vibrio cholerae causes an enhancement of the per cent of attached NDV virions. This enhancement does not depend on the multiplicity of infection.
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Classification of Cell Receptors

1991
This manuscript constitutes a first attempt to categorize the cell receptors. Based on evolutionary and biological characteristics, it is possible to classify ligand-receptor units into original families. Certain dynamic patterns that could not be classified previously lead us towards the ligand-receptor unit.
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T cell receptor antagonist peptides induce positive selection

Cell, 1994
K. Hogquist   +5 more
semanticscholar   +1 more source

NK CELL RECEPTORS

Annual Review of Immunology, 1998
▪ Abstract  NK cells are regulated by opposing signals from receptors that activate and inhibit effector function. While positive stimulation may be initiated by an array of co-stimulatory receptors, specificity is provided by inhibitory signals transduced by receptors for MHC class I.
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Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936

Leukemia, 2003
J. Dongen   +22 more
semanticscholar   +1 more source

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