Results 131 to 140 of about 615,997 (368)

Experimental immunology<br>Influence of polysaccharide fraction C isolated from <i>Caltha palustris</i> L. on T and B lymphocyte subsets in mice [PDF]

, 2012
Agnieszka Suszko, Marianna Szczypka, Magdalena Lis, J. Kuduk‐Jaworska, Bożena Obmińska‐Mrukowicz   +4 more
openalex   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Relationship Between Peripheral Blood T Lymphocyte Subsets and Prognosis of Patients with Advanced Non-small Cell Lung Cancer Treated with Camrelizumab

Zhongliu Fangzhi Yanjiu
Objective To explore the relationship between peripheral blood T lymphocyte subsets and prognosis of patients with advanced non-small cell lung cancer (NSCLC) who received treatment with camrelizumab.
DONG Changhong, FENG Yan, JIANG Yanting, GAO Jie, JIANG Xiaodong   +4 more
doaj   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Decreased Counts of T Lymphocyte Subsets Predict Prognosis in SARS-CoV-2-Infected Pneumonia in Wuhan, China: A Retrospective Study

, 2020
Wanli Jiang, Zhi Zeng, Di Fan, Ying Zhang, Zuxin Chen, Wubian Jiang, Songping Xie, Hao Xia, Yingan Jiang, Xinan Liu, Xiaoxiong Liu   +10 more
openalex   +2 more sources

Assessment of T-cell subsets and procalcitonin for diagnosing and stratifying severity in community acquired pneumonia

Scientific Reports
Accurate risk stratification in community-acquired pneumonia (CAP) is essential for guiding timely and effective clinical management. This study evaluated whether the combined assessment of circulating T-lymphocyte subsets (T-cell subsets) and serum ...
Fuquan Qi, Yaoyao Zheng, Shuxian Zhang, Hua Yang   +3 more
doaj   +1 more source

Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients

Frontiers in Immunology
PurposeThis study aimed to construct a risk predictive model for acute kidney injury in sepsis based on peripheral blood lymphocyte subsets.MethodsThis prospective study included patients with sepsis admitted to the ICU from March to August 2024 (483 for
Leyi Wang, Qi Liu, Changdong Wu, Ming Hou, Zhiwei Li   +4 more
doaj   +1 more source

Oligoclonality of Rat Intestinal Intraepithelial T Lymphocytes: Overlapping TCR β-Chain Repertoires in the CD4 Single-Positive and CD4/CD8 Double-Positive Subsets [PDF]

, 1999
Lars Helgeland, Finn–Eirik Johansen, Jon O. Utgaard, John Torgils Vaage, Per Brandtzæg   +4 more
openalex   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source