Results 261 to 270 of about 615,997 (368)

A novel subset of human lymphocytes with a T cell receptor-gamma complex. [PDF]

, 1987
S Jitsukawa, Florence Faure, Marta M. Lipinski, Frédéric Triebel, Thierry Hercend   +4 more
openalex   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source

Gut microbiota regulation of T lymphocyte subsets during systemic lupus erythematosus. [PDF]

BMC Immunol
Lian FP, Zhang F, Zhao CM, Wang XX, Bu YJ, Cen X, Zhao GF, Zhang SX, Chen JW.   +8 more
europepmc   +1 more source

Association of 1661A/G Cytotoxic T lymphocyte Antigen-4 (CTLA-4) Gene Polymorphism With a Clinical Subset of Iranian Children With Systemic Lupus Erythematosus [PDF]

, 2014
Shirin Farivar, Masoud Dehghan Tezerjani, Neda Parvini, Reza Shiari   +3 more
openalex   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Erratum for "Peripheral and intestinal T lymphocyte subsets in dogs with chronic inflammatory enteropathy". [PDF]

J Vet Intern Med
europepmc   +1 more source

Amelioration of T lymphocyte subsets, inflammatory factors and gastrointestinal function by traditional Chinese medicine rehabilitation management in postoperative chemotherapy for lung cancer. [PDF]

J Med Biochem
Zou X, Tang Y, Shi P.
europepmc   +1 more source

GLUL Confers Perivascular Cancer‐Associated Fibroblasts With Pro‐Angiogenic Capacity to Promote Glioma Progression

Advanced Science, EarlyView.
Schematic illustration of the proposed model. Primary CAFs are isolated from fresh human GBM specimens according to established protocols. GLUL is essential for pro‐angiogenic capacity of CAFs through its impact on the PI3K/AKT pathway. GLUL enhances the pro‐angiogenic capacity of CAFs, driving aberrant tumor vasculature that fuels tumor growth ...
Qing Zhang, Yida Liu, Zhi Zhang, Yang Wang, Fusheng Liu   +4 more
wiley   +1 more source

Impact of oxaliplatin and trastuzumab combination therapy on tumor markers and T lymphocyte subsets for advanced gastric cancer. [PDF]

World J Gastrointest Oncol
Zheng CW, Yang YM, Yang H.
europepmc   +1 more source