Results 111 to 120 of about 724,385 (326)

LYMPHOCYTE SUBPOPULATION PROFILE IN YOUNG MEN WITH METABOLIC SYNDROME

Медицинская иммунология, 2016
Metabolic syndrome is a chronic subclinical inflammation. Published data on the immune state in metabolic syndrome are inconsistent, and, moreover, the gender features of metabolic syndrome are not described in details.
V. A. Sumerkina, L. F. Telesheva, E. S. Golovneva, S. V. Kvyatkovskaya, E. E. Dvorchik   +4 more
doaj   +1 more source

Cyclophosphamide-sensitive T lymphocytes suppress the in vivo generation of antigen-specific cytotoxic T lymphocytes

Journal of Experimental Medicine, 1977
Murine T lymphocytes sensitized in vitro against either allogeneic lymphocytes or syngeneic hapten-conjugated lymphocytes do differentiate into highly effective cytotoxic T lymphocytes (CTL) (1-3).
M. Röllinghoff, A. Starzinski-Powitz, K. Pfizenmaier, H. Wagner   +3 more
semanticscholar   +1 more source

A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions

Advanced Healthcare Materials, EarlyView.
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan, Partho Protim Adhikary, Dana Wörz, Sarah Hedtrich   +3 more
wiley   +1 more source

Evaluation of antigen specific recognition and cell mediated cytotoxicity by a modified lysispot assay in a rat colon carcinoma model

Journal of Experimental & Clinical Cancer Research, 2012
Background Antigen-specific CD8+ cytotoxic T lymphocytes represent potent effector cells of the adaptive immune response against viruses as well as tumours.
Bordignon Valentina, Cordiali-Fei Paola, Rinaldi Monica, Signori Emanuela, Cottarelli Andrea, Zonfrillo Manuela, Ensoli Fabrizio, Rasi Guido, Fuggetta Maria   +8 more
doaj   +1 more source

Capacity of different cell types to stimulate cytotoxic T lymphocyte precursor cells in the presence of interleukin 2 [PDF]

, 1984
Plastic-adherent cells enriched for dendritic cells (AC) were found to be among the most potent stimulator cells for the activation of cytotoxic T lymphocytes (CTL) in vitro in the presence of interleukin 2 (IL 2) and a constant second set of allogeneic ...
Dröge, W., Falk, Werner, Moyers, C., Männel, D. N., Panknin, S., Schmidt, H., Wehrmaker, A.   +6 more
core  

Histocompatibility antigen-activated cytotoxic T lymphocytes. II. Estimates of the frequency and specificity of precursors

Journal of Experimental Medicine, 1977
Using limiting dilutions of responding cells in mouse mixed leukocyte cultures, we obtained direct estimates of the minimum frequency of precursors of cytotoxic T lymphocytes (CTL.P) for a variety of antigens.
K. Lindahl, Darcy B. Wilson
semanticscholar   +1 more source

Increased Anti‐Psoriatic Effect of Anti‐Inflammatory Dendrimers Using Fluid Catanionic Vesicle‐Based Topical Formulations

Advanced Healthcare Materials, EarlyView.
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Hélène Labie, Stéphanie Cassel, Séverine Fruchon, Anne‐Marie Caminade, Michel Simon, Rémy Poupot, Cédric‐Olivier Turrin, Muriel Blanzat   +10 more
wiley   +1 more source

Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells

eLife, 2017
The differentiation of naive CD8 T cells into effector cytotoxic T lymphocytes upon antigen stimulation is necessary for successful antiviral, and antitumor immune responses.
Alexandria C Wells, Keith A Daniels, Constance C Angelou, Eric Fagerberg, Amy S Burnside, Michele Markstein, Dominique Alfandari, Raymond M Welsh, Elena L Pobezinskaya, Leonid A Pobezinsky   +9 more
doaj   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

A model for the differentiation of human natural killer cells. Studies on the in vitro activation of Leu-11+ granular lymphocytes with a natural killer-sensitive tumor cell, K562. [PDF]

, 1985
A subpopulation of low density granular lymphocytes that express the natural killer (NK) cell-associated Leu-11 antigen (IgG Fc receptor) were stimulated directly by coculture with an NK-sensitive tumor cell, K562.
Lanier, LL, Phillips, JH
core