Immune composition of the mononuclear cell fraction of human umbilical cord blood. [PDF]
Front ImmunolKikuta K +7 more
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A Machine Learning-Based Scoring System to Identify High Immunoactivity Microsatellite Stability Tumors by Quantifying Similarity to Microsatellite Instability-High Tumors in Colorectal Cancers: Development and Quantitative Study. [PDF]
JMIR Form ResYan H +7 more
europepmc +1 more source
Role of tertiary lymphoid structures in the tumour microenvironment and immunotherapy response of renal cell carcinoma. [PDF]
Clin Transl MedYang L +9 more
europepmc +1 more source
Common pathological mechanisms and therapeutic strategies in primary Sjogren's syndrome and primary biliary cholangitis: from tissue immune microenvironment to targeted therapy. [PDF]
Front ImmunolYe K, Yao X, Lu D, Tan C, Wang X.
europepmc +1 more source
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Reduced regulatory T lymphocytes in migraine patients
Neurological Research, 2021Objectives: Migraine is a primary headache disorder with unknown pathophysiology. Recently, many studies have suggested the role of immune dysfunction in the pathophysiology of this disorder. In this study, we investigated the percentage of regulatory T cells (Treg cells) in different migraine categories.Methods: Peripheral blood samples of 40 newly ...
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Regulatory T lymphocytes as a therapy for ischemic stroke
Seminars in Immunopathology, 2022Unrestrained excessive inflammatory responses exacerbate ischemic brain injury and impede post-stroke brain recovery. CD4+CD25+Foxp3+ regulatory T (Treg) cells play important immunosuppressive roles to curtail inflammatory responses and regain immune homeostasis after stroke.
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Regulatory Factors Produced by Lymphocytes
The Journal of Immunology, 1976Abstract Supernatant fluids of mitogen-activated human tonsil lymphocytes contain large amounts of a factor toxic to mouse L cells. This substance, with a m.w. of 80,000 ±5,000 daltons, is called α-lymphotoxin (α-LT), to differentiate it from another toxin elaborated by mitogen-activated human blood lymphocytes, called β-lymphotoxin (β ...
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Regulatory T cells in chronic lymphocytic leukemia [PDF]
Comparative Clinical Pathology, 2014 Controversial results concerning the prognostic value of the regulatory T (Treg) cell percentage in peripheral blood of chronic lymphocytic leukemia (CLL) patients have been reported in the previous studies. This study aimed to estimate the prognostic relevance of Treg cells in untreated CLL patients at diagnosis.
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The role of regulatory t lymphocytes in asthma pathogenesis [PDF]
Current Allergy and Asthma Reports, 2005 Several subtypes of regulatory or suppressive T cells have been described that can prevent activation of effector T cells in vitro and in vivo in animal models. Recent evidence suggests a deficit in suppressive activity of both CD4(+)CD25(+) regulatory T cells, and interleukin (IL)-10 producing regulatory T cells may play a role in development of ...
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T-regulatory lymphocytes and chronic viral hepatitis
Expert Opinion on Biological Therapy, 2007Both hepatitis B virus (HBV) and hepatitis C virus (HCV) can cause persistent viral infection in humans. Chronic infection is associated with a risk of cirrhosis and hepatocellular carcinoma. The cause of chronic infection is unknown. A large body of evidence suggests that a failure of the adaptive immune response is critical in the establishment of ...
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