Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang+5 more
wiley +1 more source
Lack of detection of aluminium-reactive T-lymphocytes in patients with SCIT-induced granulomas. [PDF]
Hoffmann SS+3 more
europepmc +1 more source
The tumor microenvironment‐responsive nanoagonists are developed using an organic–inorganic copolymer composed of the polymer (PC6AB) and manganous phosphate ionic oligomers (MnP). PC6AB with membranolytic activity selectively interacts with tumor cell membranes to induce immunogenic cell death, while MnP activates the STING pathway in immune cells ...
Shiming Zhang+14 more
wiley +1 more source
Generation of ex vivo autologous hematopoietic stem cell-derived T lymphocytes for cancer immunotherapy. [PDF]
Maneechai K+5 more
europepmc +1 more source
Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng+10 more
wiley +1 more source
Tissue adaptation of CD4 T lymphocytes in homeostasis and cancer. [PDF]
Pereira MVA+4 more
europepmc +1 more source
Irreversible electroporation synergizes with oncolytic virus enhances the infiltration of cytotoxic T lymphocytes in the tumor immune microenvironment: a leap from focal therapy to immunotherapy for prostate cancer. [PDF]
Xia ZY+5 more
europepmc +1 more source
Regulatory T lymphocytes in traumatic brain injury. [PDF]
Shan J, Shi R, Hazra R, Hu X.
europepmc +1 more source
Evaluation of PD-1 and interleukin-10-receptor expression by T lymphocytes in malignant and benign pleural effusions. [PDF]
Mosleh B+9 more
europepmc +1 more source