Results 191 to 200 of about 688,743 (255)

Unfolding Immune Dysregulation in COPD: Identification of a Three-Gene Signature and Functional Validation of <i>TCF7</i> in Human Lung Tissue and T Lymphocytes. [PDF]

Int J Mol Sci
Wang Z, Yang Y, Wang L, Luo Z.
europepmc   +1 more source

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

CD26 + CD39 - CD73 + CD4 + T lymphocytes decrease after HIV-1 infection but show an intrinsic association with low viral replication and high CD4 + T-cell count. [PDF]

Chin Med J (Engl)
Zhang X, Jin J, Xu Q, Zhu A, Ding N, Liu Z, Yuan L, Lu X, Li Z, Wang R, Ma Z, Xia W, Zhang T, Su B.   +13 more
europepmc   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

Activated Interferon-γ-Positive T Lymphocytes and Cytokine Signatures in Patients With Postinfectious Cough. [PDF]

MedComm (2020)
Deng Z, Song T, Ding W, Luo W, Xie J, Wu H, Zhong N, Lai K.   +7 more
europepmc   +1 more source

CD39 Expression in Peripheral CD4+ T Lymphocytes Is Associated With Disease Activity in Patients With Systemic Lupus Erythematosus. [PDF]

J Immunol Res
Jin H, Tang L.
europepmc   +1 more source

Editorial: Mechanisms of early intracellular signaling in T lymphocytes. [PDF]

Front Immunol
Aguado E, Arbulo-Echevarria MM, Compeer EB.   +2 more
europepmc   +1 more source

HLA-DR+ CD8+ T lymphocytes as an alternative T-cell activation marker in pediatric HLH: A real-life study. [PDF]

Pediatr Allergy Immunol
Triaille C, Fernandez I, Touzot F.
europepmc   +1 more source

Development of Thymic Organoids Heterotopically to Educate and Induce T Lymphocytes. [PDF]

Immun Inflamm Dis
Wang X, Yu S, Qiu Y, Yang J, Liu F, Zhou X.   +5 more
europepmc   +1 more source

Small Messengers: Glioblastoma-Derived Extracellular Vesicles Modulate γδ T Lymphocytes Through a MIC-Dependent Mechanism. [PDF]

Biology (Basel)
Rosato M, Saibene Vélez P, Infante Cruz A, Pibuel MA, Fuentes F, Vermeulen M, Iturrizaga J, Espil PE, Berner S, Salamone GV, Jancic CC.   +10 more
europepmc   +1 more source